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PANCE: Cardiovascular System

PANCE · Work through your exam, one topic at a time.

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Cardiovascular System

Core concepts

Organize cardiovascular questions into four buckets: ischemia, pump failure, rhythm, and vascular catastrophe.

Ischemia: troponin rises within hours and peaks near 24 hours, so a single early normal value never excludes myocardial infarction. STEMI shows ST elevation in contiguous leads with reciprocal depression; pericarditis shows diffuse ST elevation, PR depression, and pleuritic positional pain.

Pump failure: BNP supports but does not establish the diagnosis. HFrEF is a dilated ventricle with reduced ejection fraction; HFpEF is a stiff ventricle with preserved ejection fraction, typically in an older hypertensive patient.

Murmurs: aortic stenosis is a crescendo-decrescendo systolic murmur radiating to the carotids; mitral regurgitation radiates to the axilla; mitral stenosis gives an opening snap and diastolic rumble; hypertrophic cardiomyopathy softens with squatting and handgrip and intensifies with Valsalva and standing.

Rhythm: an unstable tachyarrhythmia means electricity, a stable one means drugs; atrial fibrillation needs rate control plus stroke-risk stratification.

Vascular: aortic dissection is tearing pain with a pulse or blood pressure differential, and thrombolytics are contraindicated.

Traps

  • Dismissing atypical chest pain in a diabetic or older adult without an ECG.
  • Excluding dissection because the chest radiograph was normal.
  • Giving nitrates or aggressive beta blockade to a hypotensive patient with right ventricular infarction or acute decompensation.
  • Treating every pericardial effusion with a needle.

Rule of thumb

ST elevation in II, III, and aVF with reciprocal change in I and aVL is an inferior STEMI; if that patient is hypotensive, suspect right ventricular involvement and give a fluid bolus rather than nitroglycerin.