PANCE study plan
PANCE · Give each week a clear focus.
8 weeks · About 7 hours per week
Cardiovascular system
Differentiate the four major valvular lesions by auscultatory timing, location, and radiation, and name the confirmatory imaging study for each
Distinguish heart failure with reduced ejection fraction from heart failure with preserved ejection fraction and select guideline-directed first-line pharmacotherapy for each
Interpret ECG tracings for ST-elevation myocardial infarction, atrial fibrillation, and ventricular tachycardia, and state the immediate intervention for each
Compare anticoagulation and rate-versus-rhythm strategies for atrial fibrillation using stroke-risk stratification
Order the initial workup for a patient with syncope and stratify by high-risk features warranting admission
Your checkpoint
Score at least 70% on a 40-question cardiovascular self-assessment and submit a one-page error log that categorizes every missed item by mechanism (knowledge gap, misread, or reasoning error).
Cardiovascular system & Pulmonary system
Apply acute coronary syndrome pathways, including timing of reperfusion and choice of antiplatelet and anticoagulant therapy
Select empiric antibiotic therapy for community-acquired pneumonia stratified by outpatient versus inpatient versus ICU setting
Distinguish asthma from chronic obstructive pulmonary disease using spirometry and symptom pattern, and outline step-up controller therapy
Identify life-threatening causes of acute dyspnea and state the first stabilizing maneuver for tension pneumothorax and massive pulmonary embolism
Stage obstructive lung disease severity and match inhaled therapy to stage and exacerbation history
Your checkpoint
Complete a timed 50-question mixed cardiovascular and pulmonary block at 70% or better, then rewrite the rationale for each missed question in your own words.
Pulmonary system & Musculoskeletal system
Evaluate suspected pulmonary embolism using pretest probability tools and interpret D-dimer results in low-, moderate-, and high-risk patients
Localize joint pain as intra-articular versus periarticular using passive range-of-motion and provocative maneuvers
Differentiate rheumatoid arthritis from osteoarthritis and gout, and select initial disease-modifying therapy for rheumatoid arthritis
Apply fracture decision rules to ankle and knee injuries and identify which patients require imaging
Screen for red-flag features in acute low back pain and outline emergent management of cauda equina syndrome
Your checkpoint
Build a 25-card spaced-repetition deck covering pulmonary and musculoskeletal diagnostic criteria, then pass a 30-question quiz on those domains at 75% or better.
Musculoskeletal system & Dermatologic system and eyes, ears, nose, and throat
Classify skin lesions by morphology and primary configuration, and apply pigment-lesion warning features to decide on biopsy referral
Differentiate psoriasis, atopic dermatitis, tinea, and cellulitis by distribution and surface characteristics, and select first-line treatment for each
Distinguish acute otitis media from otitis externa and identify the examination findings that mandate drainage or referral
Recognize peritonsillar abscess and epiglottitis and state the airway and antibiotic steps for each
Select initial imaging for suspected fracture or ligamentous injury when decision rules are inconclusive
Your checkpoint
Complete a timed 60-question block spanning cardiovascular, pulmonary, musculoskeletal, and dermatologic/ENT content at 70% or better, with every dermatology image-free vignette re-derived from morphology alone.
Genitourinary system and renal system & Gastrointestinal system and nutrition
Stage acute kidney injury by severity criteria and distinguish prerenal, intrinsic, and postrenal causes using urinalysis and fractional excretion indices
Differentiate nephrotic from nephritic syndrome by urinalysis, complement levels, and associated systemic findings
Choose empiric and definitive therapy for uncomplicated cystitis, pyelonephritis, and complicated urinary tract infection based on risk factors
Distinguish gastroesophageal reflux disease, peptic ulcer disease, and functional dyspepsia, and apply testing and eradication strategy for Helicobacter pylori
Localize an upper versus lower gastrointestinal bleed and state the initial resuscitation and endoscopic timing for each
Your checkpoint
Write a two-page comparison table for acute kidney injury versus chronic kidney disease and for upper versus lower gastrointestinal bleeding, then score 75% or better on a 30-question quiz over both domains.
Gastrointestinal system and nutrition & Reproductive system & Endocrine system
Differentiate biliary colic, acute cholecystitis, and acute pancreatitis by history, laboratory pattern, and imaging choice
Apply colorectal cancer screening options and intervals to patients stratified by age and family history
Evaluate abnormal uterine bleeding and first-trimester bleeding by pregnancy status and hemodynamic stability
Diagnose polycystic ovary syndrome and select an appropriate contraceptive and ovulation-induction strategy
Classify thyroid dysfunction by thyroid-stimulating hormone and free thyroxine pattern and select treatment for each pattern
Manage diabetic ketoacidosis with a fluid, insulin, and potassium protocol and calculate the anion gap to track resolution
Your checkpoint
Deliver a one-page anion gap and thyroid-pattern decision sheet plus a recorded 10-minute teach-back on first-trimester bleeding, then score 75% or better on a 40-question block covering gastrointestinal, reproductive, and endocrine content.
Neurologic system & Psychiatry and behavioral medicine & Hematologic system
Localize an acute stroke syndrome by vascular territory and identify the treatment window and contraindications for thrombolysis
Differentiate migraine, cluster headache, and subarachnoid hemorrhage by onset, associated features, and imaging strategy
Screen for major depression and substance use disorder using validated instruments and select first-line pharmacotherapy with monitoring plan
Interpret complete blood count with iron studies and reticulocyte index to classify microcytic and macrocytic anemias
Identify the reversal agent and urgent step for each major anticoagulant in a bleeding patient
Distinguish generalized from focal seizure types and select initial monotherapy
Your checkpoint
Complete 50 mixed neurologic, psychiatric, and hematologic questions at 70% or better and produce a one-page quick-reference sheet mapping anemia patterns and anticoagulant reversal agents.
Infectious diseases & Cardiovascular system & Pulmonary system & Musculoskeletal system & Gastrointestinal system and nutrition & Genitourinary system and renal system & Reproductive system & Endocrine system & Neurologic system & Psychiatry and behavioral medicine & Hematologic system & Dermatologic system and eyes, ears, nose, and throat
Select empiric antibiotic therapy by infection site and patient risk factors, and adjust for resistance patterns and allergy
Interpret human immunodeficiency virus screening and staging tests and identify indications for opportunistic infection prophylaxis
Recognize sepsis and septic shock and apply the time-based resuscitation bundle
Re-drill your five weakest domains using the error log compiled across weeks 1 through 7
Simulate full-length test conditions to practice pacing, flagging, and time allocation per question
Your checkpoint
Complete a full-length 120-question timed mock examination covering all domains and submit a written remediation plan listing your three weakest domains with two specific actions for each.
Milestones
Week 2: Completed a timed mixed cardiac and pulmonary block at 70% or better, with an error log showing no more than two repeats of the same missed concept.
Week 4: Achieved 70% or better on a 60-question block covering the four heaviest domains (cardiovascular, pulmonary, musculoskeletal, dermatologic/ENT), confirming the front-loaded weight is solid before moving on.
Week 6: Achieved 75% or better on gastrointestinal, genitourinary/renal, reproductive, and endocrine content, and can state first-line management for the ten highest-yield conditions in those domains without notes.
Week 8: Scored 70% or better on the full-length 120-question mock examination, with all twelve domains represented and a written remediation plan finalized for the final review week.