PANCE study materials
PANCE study resources

PANCE study plan

PANCE · Give each week a clear focus.

8 weeks · About 7 hours per week

Week 1

Cardiovascular system

  • Differentiate the four major valvular lesions by auscultatory timing, location, and radiation, and name the confirmatory imaging study for each

  • Distinguish heart failure with reduced ejection fraction from heart failure with preserved ejection fraction and select guideline-directed first-line pharmacotherapy for each

  • Interpret ECG tracings for ST-elevation myocardial infarction, atrial fibrillation, and ventricular tachycardia, and state the immediate intervention for each

  • Compare anticoagulation and rate-versus-rhythm strategies for atrial fibrillation using stroke-risk stratification

  • Order the initial workup for a patient with syncope and stratify by high-risk features warranting admission

Your checkpoint

Score at least 70% on a 40-question cardiovascular self-assessment and submit a one-page error log that categorizes every missed item by mechanism (knowledge gap, misread, or reasoning error).

Week 2

Cardiovascular system & Pulmonary system

  • Apply acute coronary syndrome pathways, including timing of reperfusion and choice of antiplatelet and anticoagulant therapy

  • Select empiric antibiotic therapy for community-acquired pneumonia stratified by outpatient versus inpatient versus ICU setting

  • Distinguish asthma from chronic obstructive pulmonary disease using spirometry and symptom pattern, and outline step-up controller therapy

  • Identify life-threatening causes of acute dyspnea and state the first stabilizing maneuver for tension pneumothorax and massive pulmonary embolism

  • Stage obstructive lung disease severity and match inhaled therapy to stage and exacerbation history

Your checkpoint

Complete a timed 50-question mixed cardiovascular and pulmonary block at 70% or better, then rewrite the rationale for each missed question in your own words.

Week 3

Pulmonary system & Musculoskeletal system

  • Evaluate suspected pulmonary embolism using pretest probability tools and interpret D-dimer results in low-, moderate-, and high-risk patients

  • Localize joint pain as intra-articular versus periarticular using passive range-of-motion and provocative maneuvers

  • Differentiate rheumatoid arthritis from osteoarthritis and gout, and select initial disease-modifying therapy for rheumatoid arthritis

  • Apply fracture decision rules to ankle and knee injuries and identify which patients require imaging

  • Screen for red-flag features in acute low back pain and outline emergent management of cauda equina syndrome

Your checkpoint

Build a 25-card spaced-repetition deck covering pulmonary and musculoskeletal diagnostic criteria, then pass a 30-question quiz on those domains at 75% or better.

Week 4

Musculoskeletal system & Dermatologic system and eyes, ears, nose, and throat

  • Classify skin lesions by morphology and primary configuration, and apply pigment-lesion warning features to decide on biopsy referral

  • Differentiate psoriasis, atopic dermatitis, tinea, and cellulitis by distribution and surface characteristics, and select first-line treatment for each

  • Distinguish acute otitis media from otitis externa and identify the examination findings that mandate drainage or referral

  • Recognize peritonsillar abscess and epiglottitis and state the airway and antibiotic steps for each

  • Select initial imaging for suspected fracture or ligamentous injury when decision rules are inconclusive

Your checkpoint

Complete a timed 60-question block spanning cardiovascular, pulmonary, musculoskeletal, and dermatologic/ENT content at 70% or better, with every dermatology image-free vignette re-derived from morphology alone.

Week 5

Genitourinary system and renal system & Gastrointestinal system and nutrition

  • Stage acute kidney injury by severity criteria and distinguish prerenal, intrinsic, and postrenal causes using urinalysis and fractional excretion indices

  • Differentiate nephrotic from nephritic syndrome by urinalysis, complement levels, and associated systemic findings

  • Choose empiric and definitive therapy for uncomplicated cystitis, pyelonephritis, and complicated urinary tract infection based on risk factors

  • Distinguish gastroesophageal reflux disease, peptic ulcer disease, and functional dyspepsia, and apply testing and eradication strategy for Helicobacter pylori

  • Localize an upper versus lower gastrointestinal bleed and state the initial resuscitation and endoscopic timing for each

Your checkpoint

Write a two-page comparison table for acute kidney injury versus chronic kidney disease and for upper versus lower gastrointestinal bleeding, then score 75% or better on a 30-question quiz over both domains.

Week 6

Gastrointestinal system and nutrition & Reproductive system & Endocrine system

  • Differentiate biliary colic, acute cholecystitis, and acute pancreatitis by history, laboratory pattern, and imaging choice

  • Apply colorectal cancer screening options and intervals to patients stratified by age and family history

  • Evaluate abnormal uterine bleeding and first-trimester bleeding by pregnancy status and hemodynamic stability

  • Diagnose polycystic ovary syndrome and select an appropriate contraceptive and ovulation-induction strategy

  • Classify thyroid dysfunction by thyroid-stimulating hormone and free thyroxine pattern and select treatment for each pattern

  • Manage diabetic ketoacidosis with a fluid, insulin, and potassium protocol and calculate the anion gap to track resolution

Your checkpoint

Deliver a one-page anion gap and thyroid-pattern decision sheet plus a recorded 10-minute teach-back on first-trimester bleeding, then score 75% or better on a 40-question block covering gastrointestinal, reproductive, and endocrine content.

Week 7

Neurologic system & Psychiatry and behavioral medicine & Hematologic system

  • Localize an acute stroke syndrome by vascular territory and identify the treatment window and contraindications for thrombolysis

  • Differentiate migraine, cluster headache, and subarachnoid hemorrhage by onset, associated features, and imaging strategy

  • Screen for major depression and substance use disorder using validated instruments and select first-line pharmacotherapy with monitoring plan

  • Interpret complete blood count with iron studies and reticulocyte index to classify microcytic and macrocytic anemias

  • Identify the reversal agent and urgent step for each major anticoagulant in a bleeding patient

  • Distinguish generalized from focal seizure types and select initial monotherapy

Your checkpoint

Complete 50 mixed neurologic, psychiatric, and hematologic questions at 70% or better and produce a one-page quick-reference sheet mapping anemia patterns and anticoagulant reversal agents.

Week 8

Infectious diseases & Cardiovascular system & Pulmonary system & Musculoskeletal system & Gastrointestinal system and nutrition & Genitourinary system and renal system & Reproductive system & Endocrine system & Neurologic system & Psychiatry and behavioral medicine & Hematologic system & Dermatologic system and eyes, ears, nose, and throat

  • Select empiric antibiotic therapy by infection site and patient risk factors, and adjust for resistance patterns and allergy

  • Interpret human immunodeficiency virus screening and staging tests and identify indications for opportunistic infection prophylaxis

  • Recognize sepsis and septic shock and apply the time-based resuscitation bundle

  • Re-drill your five weakest domains using the error log compiled across weeks 1 through 7

  • Simulate full-length test conditions to practice pacing, flagging, and time allocation per question

Your checkpoint

Complete a full-length 120-question timed mock examination covering all domains and submit a written remediation plan listing your three weakest domains with two specific actions for each.

Milestones

Week 2: Completed a timed mixed cardiac and pulmonary block at 70% or better, with an error log showing no more than two repeats of the same missed concept.

Week 4: Achieved 70% or better on a 60-question block covering the four heaviest domains (cardiovascular, pulmonary, musculoskeletal, dermatologic/ENT), confirming the front-loaded weight is solid before moving on.

Week 6: Achieved 75% or better on gastrointestinal, genitourinary/renal, reproductive, and endocrine content, and can state first-line management for the ten highest-yield conditions in those domains without notes.

Week 8: Scored 70% or better on the full-length 120-question mock examination, with all twelve domains represented and a written remediation plan finalized for the final review week.