Oral and Maxillofacial Internal Medicine: Endodontics, Periodontics, Oral Mucosal Diseases
This domain bundles endodontics, periodontics and oral mucosal disease - the diagnostic core of the exam, where one lesion may be benign, premalignant or infectious.
Endodontics
- Working length sits 0.5–1.0 mm short of the radiographic apex; apex locators are unreliable with pus or blood in the canal.
- Sodium hypochlorite 0.5–5.25% dissolves organic tissue and is antimicrobial; 17% EDTA removes the smear layer; chlorhexidine is a final rinse but must never be mixed with hypochlorite (brown precipitate).
- Hypochlorite extrusion causes sudden pain, swelling and possible airway compromise - stop, irrigate with saline, monitor.
- Single- versus multiple-visit treatment depends on infection status, not convenience.
Periodontics
Probing depth is not attachment loss: CAL = PD + recession. The 2018 classification stages severity (I–IV) and grades progression (A–C). Scaling and root planing is the foundation; adjunctive systemic antibiotics are reserved for specific aggressive or necrotising cases.
Mucosal disease
- Leukoplakia is a diagnosis of exclusion with roughly 1% malignant transformation; biopsy is mandatory.
- Oral lichen planus shows bilateral Wickham striae, typically on buccal mucosa; erosive forms need biopsy and follow-up.
- Pemphigus vulgaris: suprabasal intraepithelial split with intercellular IgG. Mucous membrane pemphigoid: subepithelial split with linear IgG/C3 at the basement membrane.
- Pseudomembranous candidiasis wipes off leaving erythema; denture stomatitis and angular cheilitis are common variants.
Worked example
A 50-year-old smoker has a painless 2 cm red-and-white, non-homogeneous lesion on the lateral tongue present for three months. The lateral tongue is the highest-risk site, non-homogeneous leukoplakia and erythroplakia carry high dysplasia risk, and smoking multiplies it. Correct action is incisional biopsy with referral - not observation and not an antifungal trial.
Traps
Calling every white patch candidiasis; treating erosive lichen planus with antibiotics; forgetting that erythroplakia transforms more often than homogeneous leukoplakia.