ABA Critical Care flashcards
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- Berlin ARDS criteria
- Acute onset within one week, bilateral opacities, PEEP at least 5 cmH2O, and PaO2/FiO2 no more than 300; severity is mild 201-300, moderate 101-200, severe 100 or less.
- Lung-protective tidal volume
- Set tidal volume at 6 mL/kg predicted body weight, keep plateau pressure at or below 30 cmH2O, and target driving pressure at or below 15 cmH2O.
- Rapid shallow breathing index
- Divide respiratory rate by tidal volume in liters; a value below 105 predicts successful spontaneous breathing trial, although clinical judgment and other weaning criteria remain necessary.
- Auto-PEEP management
- Reduce respiratory rate, shorten inspiratory time, and allow longer expiration; treat with lower tidal volume and identify causes such as airflow obstruction or high minute ventilation.
- Mean arterial pressure formula
- Calculate MAP as diastolic pressure plus one third of the pulse pressure, or as systolic plus twice diastolic divided by three; septic shock targets at least 65 mmHg.
- Cardiac tamponade signs
- Hypotension, muffled heart sounds, and elevated jugular venous pressure form Beck triad; pulsus paradoxus and echocardiographic diastolic chamber collapse support the diagnosis.
- Fluid responsiveness assessment
- Passive leg raise or stroke volume variation can predict fluid responsiveness; a rise in stroke volume or cardiac output greater than 10 percent suggests the patient will benefit from volume.
- Post-arrest hemodynamic target
- After cardiac arrest, target a mean arterial pressure of 65 to 80 mmHg, avoid hyperoxia and hypocapnia, and provide targeted temperature control for comatose survivors.
- Cerebral perfusion pressure
- CPP equals mean arterial pressure minus intracranial pressure; typical targets are 60 to 70 mmHg while keeping intracranial pressure below about 20 to 22 mmHg.
- Status epilepticus sequence
- Give a benzodiazepine first, then levetiracetam, fosphenytoin, or valproate; refractory seizures require propofol, midazolam, or pentobarbital infusion with airway support.
- CAM-ICU delirium features
- Delirium is identified by acute change or fluctuation, inattention, altered level of consciousness, and disorganized thinking; the CAM-ICU applies these features at the bedside.
- KDIGO AKI definition
- AKI is a creatinine rise of at least 0.3 mg/dL within 48 hours, at least 1.5 times baseline within 7 days, or urine output below 0.5 mL/kg/h for 6 hours.
- Anion gap formula
- Anion gap equals sodium minus chloride plus bicarbonate; normal is about 8 to 12 mmol/L, and the delta-delta helps identify mixed metabolic acid-base disorders.
- Winter formula
- Expected PaCO2 equals 1.5 times bicarbonate plus 8, with a range of plus or minus 2; deviation suggests an additional respiratory acid-base disorder.
- Hyponatremia correction limit
- Correct chronic hyponatremia by no more than 8 to 10 mmol/L in 24 hours; faster correction increases the risk of osmotic demyelination syndrome.
- Sepsis-3 definition
- Sepsis is suspected infection plus a SOFA score increase of at least 2; septic shock adds vasopressor need for MAP at least 65 and lactate above 2 despite fluids.
- Neutropenic fever definition
- Fever is a single temperature of at least 38.3 degrees Celsius or sustained 38.0 degrees with an absolute neutrophil count below 500 cells per microliter; start anti-pseudomonal antibiotics.
- Septic shock fluid bolus
- Give 30 mL/kg of intravenous crystalloid within 3 hours for sepsis-induced hypoperfusion, then reassess fluid responsiveness; avoid continued blind fluid loading after adequate resuscitation.
- VAP prevention bundle
- Elevate the head of bed 30 to 45 degrees, interrupt sedation daily, provide oral care, avoid unnecessary antibiotics, and assess readiness for extubation every day.
- HIT management
- For heparin-induced thrombocytopenia, stop heparin and start a non-heparin anticoagulant such as argatroban or bivalirudin; avoid platelet transfusion unless there is major bleeding.
- Massive transfusion ratio
- Use a balanced 1:1:1 ratio of red blood cells, fresh frozen plasma, and platelets for massive hemorrhage; give tranexamic acid within 3 hours when trauma-related bleeding is suspected.
- TTP treatment
- Thrombotic thrombocytopenic purpura from ADAMTS13 deficiency is treated urgently with plasma exchange and steroids; platelet transfusion is avoided unless life-threatening bleeding occurs.
- DKA diagnostic criteria
- Diabetic ketoacidosis has glucose above 250 mg/dL, ketonemia or ketonuria, pH below 7.3, bicarbonate below 18, and an elevated anion gap.
- Adrenal crisis treatment
- Give hydrocortisone 100 mg intravenously followed by 50 mg every 6 hours; use dexamethasone if ACTH stimulation testing is planned, and treat precipitating illness.
- Thyroid storm treatment
- Give a thionamide first, iodine at least 1 hour later, a beta-blocker, and glucocorticoids; identify and treat triggers such as infection or surgery.
- Abdominal compartment syndrome
- It is sustained bladder pressure above 20 mmHg with new organ dysfunction; decompress with laparotomy or percutaneous drainage and optimize volume and sedation.
- Parkland burn formula
- Estimate 2 to 4 mL/kg per percent total body surface area of lactated Ringer over 24 hours, giving half in the first 8 hours and titrating to urine output.
- Lethal trauma triad
- Hypothermia, acidosis, and coagulopathy worsen each other; damage-control resuscitation treats them with warming, hemorrhage control, balanced transfusion, and correction of acidosis.
- Refeeding syndrome prevention
- Give thiamine before feeding and monitor phosphate, potassium, and magnesium; refeeding syndrome causes dangerous hypophosphatemia, hypokalemia, and hypomagnesemia after reintroduction of nutrition.
- Acetaminophen toxicity antidote
- N-acetylcysteine is the antidote and is most effective when started within 8 hours; the Rumack-Matthew nomogram guides treatment after acute overdose.
- Decision-making capacity
- Capacity requires understanding the information, appreciating consequences, reasoning about options, and expressing a choice; it is decision-specific and not equivalent to refusing care.
- ABCDEF ICU bundle
- Assess and treat pain, use both spontaneous awakening and breathing trials, choose sedation carefully, monitor delirium, mobilize early, and engage family to improve ICU outcomes.