ABPM Public Health study materials
ABPM Public Health study resources

ABPM Public Health key terms

ABPM Public Health · Get comfortable with the vocabulary.

Incidence rate

The number of new cases of a disease that develop in a defined population during a specified time period, divided by the person-time at risk. It measures how quickly new cases arise.

Related: Prevalence, Person-time, Attack rate
Prevalence

The proportion of a population that has a disease or condition at a given point in time (point prevalence) or during a period (period prevalence). It reflects total existing burden rather than speed of new occurrence.

Related: Incidence rate, Case fatality rate
Person-time

The sum of time each individual in a cohort remains under observation and at risk, often expressed as person-years. It forms the denominator for incidence rates when follow-up length varies across people.

Related: Incidence rate, Cohort study
Attack rate

The proportion of an exposed group that becomes ill during a limited outbreak period. It is a type of incidence proportion used to characterize rapidly spreading events such as foodborne illness.

Related: Incidence rate, Outbreak investigation
Case fatality rate

The proportion of people diagnosed with a disease who die from it within a specified period. It describes severity of disease among cases rather than risk in the whole population.

Related: Prevalence, Mortality rate
Mortality rate

The number of deaths in a population during a period divided by the population size, usually scaled per 1,000 or 100,000. Crude rates can be adjusted for age to allow fair comparison.

Related: Case fatality rate, Age adjustment
Age adjustment

A statistical technique that applies a study population's age-specific rates to a standard age distribution, removing the effect of age differences so rates from different populations can be compared fairly.

Related: Mortality rate, Standardization
Relative risk

The ratio of disease risk in an exposed group to risk in an unexposed group. A value of 1.0 indicates no association; values above or below suggest increased or decreased risk.

Related: Odds ratio, Cohort study, Confounding
Odds ratio

The ratio of the odds of exposure among cases to the odds of exposure among controls. It approximates relative risk when the disease is rare and is the standard measure in case-control studies.

Related: Relative risk, Case-control study
Cohort study

An observational design that follows groups defined by exposure status over time and compares disease occurrence between them. Because exposure precedes outcome, it supports stronger causal inference than case-control designs.

Related: Relative risk, Person-time, Selection bias
Case-control study

An observational design that selects people with a disease (cases) and comparable people without it (controls), then compares past exposure histories. It is efficient for rare outcomes but vulnerable to recall bias.

Related: Odds ratio, Recall bias
Cross-sectional study

A study that measures exposure and outcome simultaneously in a population at one point in time. It estimates prevalence but generally cannot establish whether exposure preceded disease.

Related: Prevalence, Ecological study
Ecological study

An observational design in which the unit of analysis is a group rather than an individual, comparing aggregate rates across populations. Findings may not apply to individuals, a problem called ecological fallacy.

Related: Cross-sectional study, Ecologic fallacy
Ecologic fallacy

An error in reasoning where an association observed between group-level variables is assumed to hold at the individual level. Aggregate data cannot reveal individual-level relationships.

Related: Ecological study
Randomized controlled trial

An experimental study in which participants are randomly assigned to intervention or control groups. Randomization balances known and unknown confounders, making it the strongest design for testing causal effects.

Related: Confounding, Selection bias, Intention-to-treat analysis
Confounding

Distortion of an exposure-outcome association by a third variable that is associated with both and is not on the causal pathway. It can create, exaggerate, or mask a true relationship.

Related: Relative risk, Randomized controlled trial, Effect modification
Effect modification

A situation in which the magnitude of an exposure's effect on an outcome differs across levels of a third variable, such as age or sex. Unlike confounding, it is a real biological or social phenomenon to report.

Related: Confounding
Selection bias

Systematic error that arises when the people included in a study differ from those eligible in ways related to both exposure and outcome. It can distort measures of association in any study design.

Related: Cohort study, Recall bias
Recall bias

A systematic error in which people with a disease remember or report past exposures differently from people without it. It is a particular threat in retrospective case-control studies.

Related: Case-control study, Selection bias
Sensitivity

The proportion of people who truly have a condition that a screening or diagnostic test correctly identifies as positive. High sensitivity means few false negatives.

Related: Specificity, Positive predictive value
Specificity

The proportion of people who truly do not have a condition that a test correctly identifies as negative. High specificity means few false positives and supports confirmation of a diagnosis.

Related: Sensitivity, Positive predictive value
Positive predictive value

The probability that a person with a positive test result actually has the condition. It depends on disease prevalence in the tested population as well as test sensitivity and specificity.

Related: Sensitivity, Specificity, Prevalence
Lead-time bias

Apparent improvement in survival that results only from earlier detection of disease rather than from delayed death. Screening programs can appear beneficial when they merely shift the diagnosis date earlier.

Related: Sensitivity, Length bias
Length bias

The tendency of screening to detect slowly progressing disease disproportionately, because such cases remain detectable longer. This makes screened groups look like they survive longer even without true benefit.

Related: Lead-time bias
Standardization

A method for adjusting summary rates to remove the influence of a differing characteristic, usually age, so populations can be compared. Direct and indirect methods use a standard population's weights.

Related: Age adjustment, Mortality rate
Confidence interval

A range of values calculated from sample data that is likely to contain the true population parameter with a stated probability, commonly 95 percent. Its width reflects precision of the estimate.

Related: P-value, Standard error
P-value

The probability of observing a result at least as extreme as the one obtained, assuming the null hypothesis is true. It is not the probability that the null hypothesis is correct.

Related: Confidence interval, Statistical power
Statistical power

The probability that a study will detect a true effect of a given size, equal to 1 minus the type II error rate. Underpowered studies may miss real associations.

Related: P-value, Sample size
Sample size

The number of participants a study must enroll to achieve adequate precision and power. It depends on expected effect size, variability, significance level, and desired power.

Related: Statistical power, Confidence interval
Standard error

The standard deviation of a statistic's sampling distribution, estimating how much a sample estimate varies from sample to sample. It is used to build confidence intervals around estimates.

Related: Confidence interval
Intention-to-treat analysis

An analysis that includes all randomized participants in the groups to which they were assigned, regardless of adherence. It preserves randomization benefits and gives a conservative estimate of effectiveness.

Related: Randomized controlled trial
Herd immunity

Indirect protection of unvaccinated people that occurs when a sufficiently high proportion of a population is immune, reducing transmission. The threshold depends on how contagious the pathogen is.

Related: Attack rate, Outbreak investigation
Outbreak investigation

A structured public health response to excess cases of a disease, involving case finding, hypothesis generation, analytic studies, and control measures. It aims to identify the source and stop transmission.

Related: Attack rate, Herd immunity
Surveillance

The ongoing, systematic collection, analysis, and interpretation of health data used to plan, implement, and evaluate public health practice. It enables early detection of trends and outbreaks.

Related: Outbreak investigation, Notifiable disease reporting
Notifiable disease reporting

A legal requirement for clinicians and laboratories to report specified diagnoses to public health authorities. These reports feed surveillance systems that guide disease control efforts.

Related: Surveillance
Primary prevention

Measures taken before disease occurs to reduce risk in susceptible people, such as immunization, fluoridation, or health education. It aims to prevent the onset of illness entirely.

Related: Secondary prevention, Tertiary prevention
Secondary prevention

Early detection and prompt treatment of disease at a presymptomatic stage to halt progression, as with screening programs. It improves outcomes by intervening before clinical disease becomes advanced.

Related: Primary prevention, Sensitivity, Lead-time bias
Tertiary prevention

Rehabilitation and treatment that reduce disability and complications after disease has occurred. It focuses on restoring function and limiting the long-term impact of established illness.

Related: Primary prevention, Secondary prevention
Health services administration

The planning, organizing, directing, and controlling of resources to deliver health care and public health services. It balances access, quality, cost, and population needs.

Related: Surveillance, Primary prevention
Determinants of health

The range of personal, social, economic, and environmental factors that influence health status. They include income, education, physical environment, and access to care.

Related: Health disparity, Social determinants of health
Social determinants of health

Conditions in the environments where people are born, live, learn, work, and age that shape health outcomes. They include income, housing, education, and neighborhood safety.

Related: Determinants of health, Health disparity
Health disparity

A preventable difference in health status or access to care that is closely linked to social or economic disadvantage. It often reflects systemic inequities rather than biological variation.

Related: Social determinants of health, Determinants of health
Health belief model

A behavioral theory proposing that health action depends on perceived susceptibility, severity, benefits, and barriers, plus cues to action and self-efficacy. It is widely used to design health education interventions.

Related: Stages of change model, Social determinants of health
Stages of change model

A behavior change framework describing progression through precontemplation, contemplation, preparation, action, and maintenance. Interventions are matched to a person's current stage of readiness.

Related: Health belief model
Risk assessment

The systematic process of identifying hazards, characterizing exposure, and estimating the likelihood and severity of harm to human health or the environment. It informs risk management decisions.

Related: Exposure assessment, Dose-response relationship
Exposure assessment

The measurement or estimation of how, how much, how long, and how often people contact a hazardous agent. It is a critical step in environmental risk assessment and epidemiology.

Related: Risk assessment, Dose-response relationship
Dose-response relationship

The observed association between increasing levels of an exposure and increasing likelihood or severity of a health effect. Its presence strengthens causal inference in environmental and occupational studies.

Related: Risk assessment, Exposure assessment
Toxicology

The science of adverse effects of chemical, physical, or biological agents on living organisms. It uses animal and in vitro studies to characterize hazards and safe exposure levels.

Related: Risk assessment, Dose-response relationship
Sentinel event

An unexpected occurrence involving death or serious harm that signals the need for immediate investigation and response. In health care it often triggers root cause analysis.

Related: Health services administration