Arab Board Radiology Part 1 study materials
Arab Board Radiology Part 1 study resources

Arab Board Radiology Part 1 cheat sheet

Arab Board Radiology Part 1 · Keep the key ideas within reach.

Quick reference

Physics, Instrumentation, and Radiologic Technology

  • Photoelectric effect probability ∝ Z³/E³; Compton scattering probability ∝ electron density and decreases with increasing E.

  • Half-value layer (HVL) = 0.693/μ; μ is linear attenuation coefficient. HVL increases with increasing beam energy.

  • CT number (Hounsfield unit) = 1000 × (μ_tissue − μ_water)/μ_water; water = 0 HU, air = −1000 HU.

  • Nyquist theorem: sampling frequency must be ≥ 2× highest spatial frequency to avoid aliasing.

  • MRI Larmor frequency: ω = γB; γ for ¹H = 42.58 MHz/T. Precession frequency is proportional to field strength.

  • Doppler shift Δf = (2 f₀ v cosθ)/c; angle of insonation of 0° maximizes detected shift.

  • In digital radiography, detective quantum efficiency (DQE) = (SNR_out/SNR_in)² and is always ≤ 1.

  • Mammographic grid ratio typically 4:1 to 5:1; higher grid ratio increases contrast but also patient dose.

  • Ultrasound axial resolution ≈ spatial pulse length/2 = (n × λ)/2, where n is number of cycles per pulse.

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Radiation Biology, Radiation Protection, and Safety

  • Linear energy transfer (LET) is higher for alpha particles and neutrons than for X-rays; high-LET radiation has higher relative biological effectiveness (RBE).

  • Cell survival curve: linear-quadratic model S = e^(−αD − βD²); α/β ratio is low for late-responding tissues (~3 Gy) and high for early-responding tissues (~10 Gy).

  • Law of Bergonié and Tribondeau: radiosensitivity is greatest in cells that are undifferentiated, rapidly dividing, and have a long mitotic future.

  • Effective dose (E) = Σ w_T × H_T; tissue weighting factors sum to 1.0. Gonads and red marrow have high w_T.

  • Annual occupational effective dose limit (ICRP): 20 mSv averaged over 5 years, with no single year exceeding 50 mSv.

  • ALARA: dose optimization using time, distance, and shielding; intensity follows inverse-square law (I ∝ 1/d²).

  • Pregnancy: lead apron 0.5 mm Pb reduces fetal dose; typical fetal dose from a chest CT is <10 mGy.

  • Stochastic effects (cancer, hereditary) have no threshold; deterministic effects (skin erythema, cataract) have thresholds (e.g., ~0.5 Gy for cataracts).

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Contrast Media, Pharmacology, and Adverse Reactions

  • Iodinated contrast osmolality: high-osmolar (~1500–2000 mOsm/kg), low-osmolar (~600–800), iso-osmolar (~290). Lower osmolality reduces osmotic nephrosis and pain.

  • Gadolinium-based contrast agents: macrocyclic agents are more stable than linear agents; avoid in severe renal impairment (eGFR <30) due to nephrogenic systemic fibrosis risk.

  • Anaphylactoid reactions are non-IgE mediated; treat with epinephrine IM 0.3–0.5 mg (1:1000) for severe reactions.

  • Metformin: current guidelines do not require withholding if eGFR ≥30; recheck renal function if contrast given in acute kidney injury setting.

  • Contrast-induced acute kidney injury (CI-AKI) risk is increased with eGFR <30, diabetes, dehydration, and high contrast volume.

  • Barium sulfate is contraindicated if bowel perforation or obstruction is suspected; use water-soluble iodinated contrast instead.

  • Ultrasound microbubble contrast agents are blood-pool agents; contraindicated in right-to-left shunt and severe pulmonary hypertension.

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Basic Sciences Relevant to Radiology (Anatomy, Physiology, Pathology)

  • Liver segments are defined by the Couinaud classification based on portal and hepatic vein anatomy; segment I is the caudate lobe.

  • The nephron: glomerulus filters plasma; proximal tubule reabsorbs ~65% of filtered sodium and water.

  • Frank-Starling law: stroke volume increases with increased end-diastolic volume up to a physiologic limit.

  • Types of cell death: necrosis (passive, inflammatory) vs apoptosis (programmed, non-inflammatory).

  • Tumor suppressor genes (e.g., TP53, RB1) require loss of both alleles (two-hit hypothesis) for carcinogenesis.

  • Oxygen-hemoglobin dissociation curve shifts right with increased 2,3-DPG, acidosis, and hyperthermia (decreased affinity).

  • Cranial nerve VII (facial) exits the stylomastoid foramen; parotid tumors can cause facial nerve palsy.

  • The thoracic duct drains into the left subclavian vein at the venous angle; chylothorax is typically left-sided.

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Chest and Cardiothoracic Imaging

  • Silhouette sign: loss of border between two structures of same density indicates they are in contact (e.g., right middle lobe opacity obscures right heart border).

  • Air bronchogram indicates alveolar filling (consolidation) with patent bronchi; its absence suggests bronchial obstruction or pleural disease.

  • Cardiothoracic ratio >0.5 on PA erect chest radiograph suggests cardiomegaly; AP view exaggerates heart size.

  • CT pulmonary angiography (CTPA) is first-line for suspected pulmonary embolism in hemodynamically stable patients; high negative predictive value.

  • Honeycombing on HRCT is a hallmark of usual interstitial pneumonia (UIP); predominantly subpleural and basal.

  • Solitary pulmonary nodule: >8 mm warrants PET/CT or tissue sampling; ≤8 mm follow Fleischner Society guidelines.

  • Aortic dissection: Stanford type A involves ascending aorta (surgical emergency); type B does not.

  • Pneumothorax on supine radiograph: deep sulcus sign (lucency at costophrenic angle).

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Abdominal and Gastrointestinal Imaging

  • Acute appendicitis on CT: enlarged appendix >6 mm, periappendiceal fat stranding, and wall enhancement.

  • Small bowel obstruction: dilated loops >3 cm, air-fluid levels, and transition point on CT.

  • Liver hemangioma: peripheral nodular enhancement with centripetal fill-in on multiphasic CT/MRI.

  • Hepatocellular carcinoma (HCC): arterial hyperenhancement with venous washout in a cirrhotic liver.

  • Pancreatic adenocarcinoma: hypoenhancing mass with ductal dilatation (double duct sign).

  • Crohn disease: transmural inflammation, skip lesions, and fistulae; ulcerative colitis: continuous mucosal involvement from rectum.

  • Bowel wall thickening >3 mm on CT is abnormal; pneumatosis intestinalis indicates intramural gas and possible ischemia.

  • Barium enema ‘apple-core’ lesion suggests colorectal carcinoma.

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Genitourinary and Gynecologic Imaging

  • Renal cell carcinoma: enhancing mass; clear cell subtype typically hypervascular and may contain fat (rarely).

  • Transitional cell carcinoma: filling defect on excretory phase CT urography; common in bladder and renal pelvis.

  • Ovarian torsion: enlarged ovary with peripheral follicles and decreased Doppler flow; surgical emergency.

  • Endometrial carcinoma: thickened endometrium (>4 mm in postmenopausal bleeding) on ultrasound; MRI for staging.

  • Prostate cancer: PI-RADS score on multiparametric MRI; score ≥3 warrants biopsy.

  • Renal stone: non-contrast CT is gold standard; stone density >1000 HU predicts poor shockwave lithotripsy response.

  • Hydrosalpinx: tubular fluid-filled structure with folded appearance; associated with infertility.

  • Testicular torsion: absent Doppler flow; radionuclide scan shows cold spot; immediate surgery required.

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Musculoskeletal Imaging

  • Osteosarcoma: aggressive bone destruction, periosteal reaction (sunburst, Codman triangle), and soft tissue mass; metaphysis of long bones.

  • Ewing sarcoma: permeative destruction, onion-skin periosteal reaction, diaphysis of long bones in children.

  • Giant cell tumor: eccentric, lytic, epiphyseal lesion in skeletally mature patients; soap-bubble appearance.

  • Rheumatoid arthritis: marginal erosions, periarticular osteopenia, symmetric polyarthritis; MCP and PIP joints.

  • Osteoarthritis: joint space narrowing, subchondral sclerosis, osteophytes, subchondral cysts; weight-bearing joints.

  • MRI bone marrow edema: low T1 and high T2/STIR signal; nonspecific but seen in trauma, infection, tumor.

  • Meniscal tear: linear high signal on T2/PD within meniscus; grade 3 indicates tear.

  • Bone scan: increased uptake in fractures, infection, metastases; highly sensitive but nonspecific.

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Neuroradiology

  • Acute ischemic stroke: CT hyperdense MCA sign; MRI DWI is most sensitive early.

  • Hemorrhage: hyperdense on non-contrast CT; MRI signal varies with age of blood (T1/T2).

  • Multiple sclerosis: periventricular ovoid lesions (Dawson fingers) oriented perpendicular to ventricles; T2/FLAIR hyperintense.

  • Glioblastoma: ring-enhancing lesion with central necrosis and surrounding edema; crosses corpus callosum (butterfly).

  • Meningioma: extra-axial, dural tail, homogeneous enhancement, may cause hyperostosis.

  • Cerebral aneurysm: CTA or MRA for detection; subarachnoid hemorrhage on CT in basal cisterns.

  • Hydrocephalus: enlarged ventricles with transependymal edema (acute) or sulcal effacement.

  • Pituitary macroadenoma: >10 mm, may cause bitemporal hemianopia and cavernous sinus invasion.

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Head and Neck Imaging

  • Thyroid nodule: ultrasound features of malignancy include microcalcifications, hypoechogenicity, irregular margins, and taller-than-wide shape.

  • Squamous cell carcinoma of head and neck: most common malignancy; nodal metastasis often cystic in HPV-related disease.

  • Parotid tumors: pleomorphic adenoma (benign, well-defined) vs mucoepidermoid carcinoma (malignant).

  • Juvenile nasopharyngeal angiofibroma: adolescent male with epistaxis; highly vascular, enhances avidly.

  • Orbital cellulitis: preseptal vs postseptal; postseptal requires urgent antibiotics and imaging.

  • Laryngeal cancer: glottic tumors present early with hoarseness; supraglottic tumors present late with nodal spread.

  • Skull base tumors: chordoma (clivus, T2 hyperintense) vs chondrosarcoma (petroclival, calcified).

  • Facial nerve schwannoma: enhancing mass in facial nerve canal; may cause facial palsy.

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Breast Imaging

  • BI-RADS categories: 0 (incomplete), 1 (negative), 2 (benign), 3 (probably benign, <2% malignancy), 4 (suspicious, 2–95%), 5 (highly suggestive, >95%), 6 (known biopsy-proven malignancy).

  • Mammographic findings of malignancy: spiculated mass, clustered pleomorphic microcalcifications, architectural distortion.

  • Ductal carcinoma in situ (DCIS): linear or branching calcifications; often no mass.

  • Ultrasound: simple cyst (anechoic, posterior enhancement) requires no further workup.

  • MRI breast: high sensitivity, used for screening high-risk women (BRCA mutation) and evaluating extent of disease.

  • Stereotactic biopsy: for calcifications; ultrasound-guided biopsy for masses.

  • Male breast cancer: subareolar mass; associated with BRCA2 and Klinefelter syndrome.

  • Density of breast tissue on mammography affects sensitivity; dense breasts reduce sensitivity and may warrant supplemental ultrasound.

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Pediatric Imaging

  • Pyloric stenosis: ultrasound shows thickened pyloric muscle (>3 mm) and elongated canal (>15 mm); target sign.

  • Intussusception: ultrasound shows target sign or pseudokidney; contrast enema is diagnostic and therapeutic.

  • Hyaline membrane disease: premature infant, ground-glass opacities, air bronchograms, low lung volumes.

  • Meconium aspiration: term infant, patchy infiltrates, hyperinflation, air leaks.

  • Neuroblastoma: abdominal mass, calcifications, crosses midline; elevated catecholamines.

  • Wilms tumor: renal mass, may have hematuria; associated with WAGR syndrome.

  • Developmental dysplasia of hip: ultrasound for screening; alpha angle <60° abnormal.

  • Pediatric radiation sensitivity: higher risk per unit dose; use ALARA, reduce kVp and mAs, shield gonads.

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Nuclear Medicine, Molecular Imaging, and Interventional Radiology

  • PET/CT with ¹⁸F-FDG: increased uptake in malignancy, infection, inflammation; brain and heart normally show high uptake.

  • Bone scan (⁹⁹mTc-MDP): sensitive for bone metastases; superscan shows diffuse uptake with absent renal uptake.

  • V/Q scan: high probability when multiple segmental mismatched defects; used when CTPA contraindicated.

  • Thyroid scan: ⁹⁹mTc-pertechnetate or ¹²³I; cold nodule requires ultrasound and possible biopsy.

  • Interventional radiology: Seldinger technique for vascular access; common femoral artery most common site.

  • TACE (transarterial chemoembolization) for HCC; Y-90 radioembolization is another option.

  • Nephrostomy: percutaneous drainage of obstructed kidney; contraindicated in uncorrected coagulopathy.

  • Radiation safety in IR: use pulsed fluoroscopy, last-image hold, and collimation to reduce dose.