Provimi i Informatizuar i Mjekësisë study materials
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Provimi i Informatizuar i Mjekësisë key terms

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Sensitivity

The proportion of people who truly have a disease and are correctly identified as positive by a test. It measures how well a test detects disease when disease is present.

Related: Specificity, Positive predictive value, Negative predictive value
Specificity

The proportion of people without a disease who are correctly identified as negative by a test. It measures how well a test rules out disease in healthy people.

Related: Sensitivity, Positive predictive value
Positive predictive value

The probability that a person with a positive test result actually has the disease. It depends strongly on how common the disease is in the tested population.

Related: Sensitivity, Specificity, Prevalence
Negative predictive value

The probability that a person with a negative test result truly does not have the disease. It rises when the disease is rare in the population tested.

Related: Sensitivity, Specificity, Prevalence
Prevalence

The total number of existing cases of a disease in a population at a given point or period, divided by the population size. It describes how widespread a condition is.

Related: Incidence, Positive predictive value
Incidence

The number of new cases of a disease arising in a population over a defined period, divided by the population at risk. It measures how fast new disease appears.

Related: Prevalence, Relative risk
Relative risk

The ratio of disease incidence in an exposed group to incidence in an unexposed group. A value above one suggests the exposure increases disease risk.

Related: Odds ratio, Incidence, Confounding
Odds ratio

The ratio of the odds of exposure among cases to the odds of exposure among controls. It estimates association strength, especially in case-control studies.

Related: Relative risk, Confounding
Confounding

A distortion of the measured association between exposure and outcome caused by a third factor linked to both. It can create apparent effects that are not real.

Related: Relative risk, Selection bias
Selection bias

A systematic error arising when the groups compared differ in ways related to the outcome because of how participants were chosen or retained. It threatens study validity.

Related: Confounding, Randomization
Randomization

The random allocation of participants to treatment or control groups so that known and unknown characteristics are balanced. It reduces bias when comparing interventions.

Related: Selection bias, Confidence interval
Confidence interval

A range of values, calculated from sample data, that is likely to contain the true population parameter with a stated probability. It expresses estimate precision.

Related: Randomization, P value
P value

The probability of observing a result at least as extreme as the one found, assuming the null hypothesis is true. It is not the probability that the hypothesis is true.

Related: Confidence interval
Pharmacokinetics

The study of how the body handles a drug over time, covering absorption, distribution, metabolism, and excretion. It links dose to drug concentration in the body.

Related: Pharmacodynamics, Half-life, Bioavailability
Pharmacodynamics

The study of what a drug does to the body, including its mechanism of action, receptor effects, and the relationship between concentration and response. It explains drug action.

Related: Pharmacokinetics, Therapeutic index
Half-life

The time required for the plasma concentration of a drug to fall by half during elimination. It guides dosing intervals and predicts how quickly a drug clears.

Related: Pharmacokinetics, Bioavailability
Bioavailability

The fraction of an administered dose of a drug that reaches the systemic circulation unchanged. Intravenous dosing is taken as complete, while oral dosing is often lower.

Related: Pharmacokinetics, First-pass metabolism
First-pass metabolism

Breakdown of an orally taken drug in the gut wall or liver before it reaches the general circulation. It can greatly reduce the effective dose absorbed.

Related: Bioavailability, Pharmacokinetics
Therapeutic index

The ratio between a drug dose that causes toxicity and a dose that produces the desired effect. A low value means the drug is risky and needs careful monitoring.

Related: Pharmacodynamics, Half-life
Informed consent

A patient's voluntary agreement to a medical intervention after receiving and understanding adequate information about its nature, benefits, risks, and alternatives. It respects patient autonomy.

Related: Patient autonomy, Medical confidentiality, Capacity
Patient autonomy

The principle that a competent patient has the right to make decisions about their own care according to personal values, even if others disagree. It underpins consent and refusal.

Related: Informed consent, Capacity
Medical confidentiality

The duty of health professionals to keep patient information private and share it only with those involved in care or when legally required. It builds trust in the clinical relationship.

Related: Informed consent
Capacity

A patient's ability to understand relevant information and appreciate the consequences of a decision about their care. It is assessed for a specific decision at a specific time.

Related: Informed consent, Patient autonomy
Medical negligence

Failure to provide the standard of care that a reasonably competent professional would give, resulting in harm to the patient. It requires a duty, a breach, causation, and damage.

Related: Informed consent, Standard of care
Standard of care

The level and type of care that a reasonably competent practitioner in the same field would provide in similar circumstances. It is the benchmark for judging negligence.

Related: Medical negligence
Triage

The process of sorting patients by urgency so that limited resources go first to those who need immediate care. It is used in emergencies and mass-casualty situations.

Related: Shock, ABCDE approach
ABCDE approach

A structured sequence for assessing critically ill patients: airway, breathing, circulation, disability, and exposure. It prioritizes life-threatening problems and is repeated as the patient changes.

Related: Triage, Shock
Shock

A state of inadequate tissue perfusion that deprives cells of oxygen and nutrients, leading to organ dysfunction. It can arise from blood loss, infection, heart failure, or allergic reaction.

Related: Triage, ABCDE approach
Sepsis

A life-threatening organ dysfunction caused by a dysregulated body response to infection. Early recognition and prompt treatment with fluids and antibiotics improve survival.

Related: Shock, ABCDE approach
Myocardial infarction

Death of heart muscle caused by sudden blockage of a coronary artery, usually from a blood clot on a ruptured plaque. It presents with chest pain and requires urgent reperfusion.

Related: Shock, Hypertension
Hypertension

Persistently elevated arterial blood pressure above defined thresholds, often without symptoms for years. It is a major risk factor for stroke, heart disease, and kidney damage.

Related: Myocardial infarction, Diabetes mellitus
Diabetes mellitus

A group of metabolic disorders marked by high blood glucose due to insufficient insulin action or secretion. Long-term complications affect the eyes, kidneys, nerves, and blood vessels.

Related: Hypertension, Pharmacokinetics
Preeclampsia

A pregnancy disorder appearing after twenty weeks with new high blood pressure and signs of organ damage such as protein in urine. It threatens both mother and fetus.

Related: Hypertension, Gestational age
Gestational age

The age of a pregnancy measured from the first day of the last menstrual period, usually expressed in completed weeks. It guides prenatal care and decisions at delivery.

Related: Preeclampsia, Apgar score
Apgar score

A rapid assessment of a newborn at one and five minutes after birth, scoring heart rate, breathing, muscle tone, reflexes, and color. It guides immediate neonatal resuscitation.

Related: Gestational age
Dehydration

A deficit of body water that impairs normal function, often from vomiting, diarrhea, or fever. In children it is assessed by signs such as dry mucous membranes and reduced skin turgor.

Related: Shock
Antimicrobial resistance

The ability of microorganisms to survive exposure to drugs that would normally kill or inhibit them. It is driven by overuse and misuse of antibiotics and threatens treatment of infections.

Related: Sepsis, Pharmacodynamics
Screening

Testing apparently healthy people to detect disease at an early, treatable stage before symptoms appear. Its value depends on test accuracy, disease burden, and available treatment.

Related: Sensitivity, Specificity, Prevalence
Electronic health record

A digital longitudinal record of a patient's health information shared across care settings. It supports clinical decisions, continuity of care, and reporting, while raising privacy concerns.

Related: Medical confidentiality, Telemedicine
Telemedicine

The delivery of clinical services at a distance using information and communication technology. It improves access to specialists but requires attention to consent, privacy, and record keeping.

Related: Electronic health record, Informed consent