FVH Pathologie flashcards
FVH Pathologie · Build recall with a focused review session.
21 cards. Read the term and the definition here. The deck at the top of this page is optional.
- Morphological diagnosis
- A structured description of a lesion by features such as organ, distribution, severity, duration and type of pathological process.
- Autolysis
- Postmortem tissue degradation that can obscure diagnostic architecture or complicate distinction between actual disease and later change.
- Immunohistochemistry
- A tissue technique identifying selected antigens using antibodies, interpreted with controls, morphology and the actual test limitations.
- Pseudomelanosis
- A postmortem discoloration involving sulfur compounds and tissue iron, distinguished from pigmentation produced by disease during life.
- Rigor mortis
- Postmortem muscle stiffening related to energy depletion and cross-bridge behavior, whose course depends on tissue and environmental conditions.
- Representative specimen
- Material selected to reflect the actual lesion and diagnostic question, with suitable identification and handling for the intended laboratory investigation.
- Coagulative necrosis
- A pattern of cell death in which tissue outlines can initially remain recognizable despite loss of viable cells.
- Interface dermatitis
- An inflammatory injury pattern involving the epidermal basal region and its interface, interpreted with other features and clinical evidence.
- Amyloid
- An extracellular protein deposit recognized through appropriate morphology and special staining, with further typing needed for its particular composition.
- Clonality
- A population pattern supporting common cellular origin, which requires context because it is not automatically synonymous with malignant disease.
- Immunophenotype
- The pattern of selected antigen expression in a cell population, assessed using appropriate validated markers and controls.
- In situ hybridization
- Detection of a selected nucleic-acid target within preserved tissue location, linking its signal to relevant cells and architecture.
- Regenerative response
- Evidence that the relevant erythropoietic system is responding to anemia, interpreted according to species, timing and the selected measurements.
- Left shift
- An increased representation of immature neutrophil forms in circulation, interpreted with mature-cell numbers, toxic change and clinical context.
- Paired fluid comparison
- A comparison of a cavity-fluid measurement with a contemporaneous relevant blood measurement to support a particular pathophysiological interpretation.
- Histological grade
- A microscopic assessment within a defined tumor-specific system, distinct from anatomical stage and not a guarantee of individual outcome.
- Neoplastic osteoid
- Bone matrix produced directly by neoplastic cells, which can support an osteosarcoma diagnosis in an appropriate pathological context.
- Sampled surgical margin
- A resection surface examined in submitted tissue sections, whose findings depend on orientation, preparation and the sampling performed.
- Megalocytosis
- Marked cellular and nuclear enlargement that can occur in relevant hepatotoxic patterns, interpreted with exposure and other pathological evidence.
- Fibrous osteodystrophy
- A skeletal change involving increased resorption and fibrous tissue replacement under the relevant endocrine and mineral circumstances.
- Analytical detection
- Identification or measurement of a target substance under specified test conditions, distinguished from proof that it caused the observed lesions.