Facharzt FMH Dermatologie und Venerologie - independent subject foundations flashcards
Facharzt FMH Dermatologie und Venerologie - independent subject foundations · Build recall with a focused review session.
20 cards. Read the term and the definition here. The deck at the top of this page is optional.
- Spongiosis
- Intercellular epidermal edema that supports an eczematous reaction pattern but must be interpreted with the actual clinical and histological differential.
- Acantholysis
- Loss of cohesion among keratinocytes that can contribute to intraepidermal separation in several acquired or inherited skin disorders.
- Interface dermatitis
- A reaction pattern involving injury near the dermoepidermal junction, interpreted with infiltrate, accompanying changes and the clinical context.
- Desmosome
- A cell-to-cell adhesion structure whose components help connect neighboring keratinocytes and can be targets in blistering disease.
- Hemidesmosome
- A basal-cell adhesion structure linking intracellular filaments with the basement-membrane region rather than joining two neighboring keratinocytes.
- Anchoring fibril
- A structural component involving type VII collagen that helps attach the basement-membrane region to underlying dermal connective tissue.
- Direct immunofluorescence
- Examination of appropriately selected tissue for deposited immunoreactants, with interpretation influenced by site, handling and the clinical setting.
- Salt-split assessment
- A method separating skin at an artificial plane to help localize immunoreactivity, interpreted alongside antigen testing and clinical features.
- Breslow thickness
- The measured vertical thickness of an invasive melanoma using the applicable pathological convention, contributing to staging and management decisions.
- Ulceration
- Loss of the overlying epidermal covering in a relevant pathological context, an important staging feature when assessed in melanoma.
- Margin-controlled surgery
- A surgical approach using mapped histological margin assessment in appropriate tumors, intended to combine clearance assessment with tissue conservation.
- Perineural invasion
- Tumor involvement of a nerve-related compartment that can influence risk assessment and management under the actual tumor framework.
- Prozone phenomenon
- An antibody-excess effect that can interfere with certain serological reactions and cause misleadingly negative results in an undiluted specimen.
- Tinea incognito
- A dermatophyte infection with morphology altered by inappropriate anti-inflammatory treatment, making clinical recognition and sampling more challenging.
- Pathergy
- An exaggerated lesion response after relatively minor trauma in certain inflammatory conditions, relevant to assessment and procedural planning.
- Genodermatosis
- An inherited condition with cutaneous manifestations that may also require evaluation of extracutaneous findings and the relevant inheritance pattern.
- Infantile hemangioma
- A vascular tumor with a characteristic postnatal growth and subsequent evolution, distinct from the behavior of a capillary malformation.
- Contact sensitization
- An immune response to an external substance that must be assessed for actual clinical relevance rather than equated with every positive test.
- Drug eruption
- A cutaneous reaction associated with a medicine exposure, classified using timing, morphology, systemic features and competing explanations.
- Clinical correlation
- Integration of clinical history, morphology, tissue findings and laboratory evidence so that one isolated result is not treated as a complete diagnosis.