Egyptian Board Hematology - independent subject foundations flashcards
Egyptian Board Hematology - independent subject foundations · Build recall with a focused review session.
20 cards. Read the term and the definition here. The deck at the top of this page is optional.
- Reticulocyte response
- A measure of young red-cell production interpreted relative to the anemia and treatment context rather than as an isolated percentage.
- Hepcidin
- A systemic iron-regulatory hormone influencing ferroportin-mediated iron export and linking absorption, storage and inflammatory signals.
- Ferroportin
- An iron-export protein whose expression and hepcidin response affect the distribution and availability of iron.
- Ineffective erythropoiesis
- Failure of adequate mature red-cell output despite erythroid activity, relevant to several nutritional, globin and marrow disorders.
- Direct antiglobulin test
- A test for immunoglobulin or complement coating of red cells, interpreted separately from serum antibody screening.
- Alloantibody
- An antibody directed at an antigen from another individual of the same species, potentially relevant to transfusion compatibility.
- Anamnestic response
- Renewed immune production after re-exposure to a previously recognized antigen, potentially explaining a delayed transfusion reaction.
- Leukoreduction
- Reduction of donor leukocytes in a blood component, which addresses selected risks but does not replace every other modification.
- Component irradiation
- Treatment of relevant cellular blood components to prevent viable donor lymphocytes from causing transfusion-associated graft-versus-host disease.
- Corrected count increment
- A platelet-response measure that accounts for the actual count change, body size and transfused platelet dose.
- ADAMTS13
- A protease involved in processing von Willebrand factor, whose severe deficiency is central to important TTP presentations.
- Lupus anticoagulant
- An assay-related antiphospholipid phenomenon that can prolong certain clotting tests despite association with thrombotic rather than simple bleeding risk.
- Mixing study
- A coagulation-assay investigation using patient and normal plasma to help assess deficiency, inhibition and relevant interference.
- Factor inhibitor
- An antibody or other inhibiting influence affecting the measured or clinical activity of a particular coagulation factor.
- Nonheparin anticoagulant
- An anticoagulant from another class considered in relevant settings such as HIT, with selection dependent on the individual context.
- Chimerism
- The measured contribution of donor and recipient cells after transplantation, interpreted with timing, method and the actual disease course.
- Graft-versus-leukemia effect
- Donor immune activity contributing to control of a hematologic malignancy after an appropriate allogeneic transplantation.
- Minimal residual disease
- A context-dependent assessment of persisting disease below conventional detection, using a specified validated method and time point.
- Differentiation syndrome
- A potentially serious inflammatory complication of certain differentiation therapies requiring recognition through the actual clinical pattern.
- Clonal hematopoiesis
- Blood-cell production from an acquired clone, which is not by itself equivalent to every overt hematologic malignancy.