HESI A2 study materials
HESI A2 study resources

HESI A2: Vocabulary and General Knowledge

HESI A2 · Work through your exam, one topic at a time.

All guide sections

Vocabulary and General Knowledge

What this section tests

This domain rewards a broad working vocabulary plus light general knowledge. Expect synonyms and antonyms, context-clue items (a word used in a sentence, with four candidate meanings), word parts (prefixes, suffixes, Greek and Latin roots), connotation (positive, negative, neutral), homophones and commonly confused pairs, simple analogies, and general-knowledge questions drawn from basic science, geography, history, and literary terms.

High-yield word parts

  • bene- good / mal- bad (beneficent, malevolent)
  • pre- before / post- after
  • anti- against / syn- together
  • -ology study of / -itis inflammation
  • -graph writing / -phobia fear
  • aud- hear / spec- look / dict- speak

Traps to expect

  • Secondary meanings. A familiar word used in an unfamiliar sense (a run in her stocking, a sharp turn).
  • Connotation mismatch. Two choices may be synonyms, but only one carries the right tone (thrifty vs. stingy).
  • Look-alike words. Emigrate/immigrate, accept/except, affect/effect, principal/principle.
  • Analogy direction. Establish the relationship first (part-to-whole, cause-to-effect, degree), then apply it in the same order.

Rule of thumb

For context items, cover the word and predict a substitute. Then check the sentence with each option; the correct choice should preserve both meaning and tone. For analogies, write your relationship as a full sentence before looking at the pairs.

Worked example

The doctor's prognosis was guarded. Using pro- (before) plus the root gnosis (knowledge), prognosis means a forecast of how a condition will develop - a prediction made before the outcome is known. Choices offering "diagnosis" (identification of the disease) are the classic distractor.