KBIT-2 study materials
KBIT-2 study resources

KBIT-2 key terms

KBIT-2 · Get comfortable with the vocabulary.

Osmosis

The net movement of water molecules across a selectively permeable membrane from a region of higher water potential to one of lower water potential, driven by solute concentration differences.

Related: Diffusion, Tonicity
Diffusion

The passive net movement of particles from an area of higher concentration to an area of lower concentration, resulting from random thermal motion until equilibrium is approached.

Related: Osmosis, Concentration Gradient
Tonicity

The ability of an external solution to cause water to enter or leave a cell, classified as hypotonic, isotonic, or hypertonic relative to the cell's internal solute concentration.

Related: Osmosis, Plasmolysis
Enzyme Active Site

The specific pocket or cleft on an enzyme's surface where substrate binds and catalysis occurs, shaped by the protein's three-dimensional folding and complementary to the substrate.

Related: Competitive Inhibition, Denaturation
Competitive Inhibition

A form of enzyme inhibition in which a molecule resembling the substrate binds the active site, blocking substrate access; its effect can be reduced by raising substrate concentration.

Related: Enzyme Active Site, Allosteric Regulation
Allosteric Regulation

Control of protein activity by a molecule binding at a site distinct from the active site, changing the protein's shape and thereby increasing or decreasing its function.

Related: Competitive Inhibition, Denaturation
Denaturation

Loss of a protein's functional three-dimensional structure caused by heat, extreme pH, or chemical agents, disrupting hydrogen bonds and other interactions without breaking peptide bonds.

Related: Enzyme Active Site, Allosteric Regulation
ATP

Adenosine triphosphate, the universal energy-carrying molecule of cells; hydrolysis of its terminal phosphate bond releases energy that powers endergonic cellular reactions and processes.

Related: Glycolysis, Chemiosmosis
Glycolysis

The anaerobic first stage of cellular respiration in which one glucose molecule is split and converted into two pyruvate molecules, yielding a net gain of two ATP and two NADH.

Related: ATP, Krebs Cycle
Krebs Cycle

A series of reactions in the mitochondrial matrix that oxidizes acetyl-CoA, releasing carbon dioxide and generating NADH, FADH2, and a small amount of ATP.

Related: Glycolysis, Chemiosmosis
Chemiosmosis

ATP synthesis driven by the flow of protons down an electrochemical gradient through ATP synthase across a membrane, typically the inner mitochondrial membrane or thylakoid membrane.

Related: ATP, Krebs Cycle
Allele

One of two or more alternative versions of a gene at a given locus, which may differ in nucleotide sequence and produce different observable traits.

Related: Genotype, Phenotype
Genotype

The particular combination of alleles an individual carries at one or more genetic loci, which together with environmental influence contributes to the observable phenotype.

Related: Allele, Phenotype
Phenotype

The observable characteristics of an organism, resulting from the interaction between its genotype and environmental factors rather than from genes alone.

Related: Genotype, Allele
Codominance

A relationship between alleles in which both are fully expressed in the heterozygote, so the phenotype shows both traits distinctly, as in human AB blood type.

Related: Incomplete Dominance, Allele
Incomplete Dominance

A relationship in which the heterozygote shows a blended intermediate phenotype between the two homozygotes, because neither allele completely masks the other.

Related: Codominance, Phenotype
Linked Genes

Genes located close together on the same chromosome that tend to be inherited together and do not assort independently, though crossing over can separate them.

Related: Crossing Over, Recombination Frequency
Crossing Over

The exchange of corresponding chromosome segments between homologous chromosomes during prophase I of meiosis, generating new combinations of alleles on a chromosome.

Related: Linked Genes, Recombination Frequency
Recombination Frequency

The proportion of offspring showing recombination between two loci, used as a measure of genetic distance and as evidence for the relative positions of genes on a chromosome.

Related: Linked Genes, Crossing Over
Homeostasis

The maintenance of a relatively stable internal environment within an organism despite external fluctuations, achieved through negative and positive feedback control systems.

Related: Negative Feedback, Osmoregulation
Negative Feedback

A control mechanism in which a change in a variable triggers a response that opposes and reverses the change, restoring the variable toward its set point.

Related: Homeostasis, Osmoregulation
Osmoregulation

The physiological control of water and solute balance in body fluids, maintaining appropriate osmotic pressure through processes such as kidney filtration and hormone-regulated reabsorption.

Related: Homeostasis, Osmosis
Action Potential

A rapid, transient reversal of membrane potential along a neuron or muscle cell, produced by sequential ion channel opening and propagated as a nerve impulse.

Related: Refractory Period, Synapse
Refractory Period

A brief interval after an action potential during which a neuron cannot fire again, ensuring impulses travel in one direction and limiting maximum firing frequency.

Related: Action Potential, Synapse
Synapse

The junction between two neurons or between a neuron and a target cell, across which a signal is transmitted chemically by neurotransmitters or electrically by gap junctions.

Related: Action Potential, Neurotransmitter
Neurotransmitter

A chemical messenger released from a presynaptic terminal that diffuses across a synaptic cleft and binds receptors on a postsynaptic cell, altering its excitability.

Related: Synapse, Action Potential
Carrying Capacity

The maximum population size of a species that a given environment can sustain indefinitely, determined by available resources, space, and other limiting factors.

Related: Limiting Factor, Exponential Growth
Limiting Factor

An environmental resource or condition that is in shortest supply relative to demand and therefore restricts the growth, distribution, or abundance of a population.

Related: Carrying Capacity, Trophic Level
Trophic Level

A position in a food chain defined by the number of energy-transfer steps from the primary producer, such as primary consumer or secondary consumer.

Related: Limiting Factor, Keystone Species
Keystone Species

A species whose influence on community structure is disproportionately large relative to its abundance, so its removal causes substantial changes to the ecosystem.

Related: Trophic Level, Carrying Capacity
Natural Selection

The differential survival and reproduction of individuals due to heritable variation in traits, causing advantageous alleles to increase in frequency across generations.

Related: Genetic Drift, Fitness
Genetic Drift

Random change in allele frequencies in a population across generations, especially strong in small populations, independent of any selective advantage.

Related: Natural Selection, Gene Flow
Gene Flow

The transfer of alleles between populations through migration of individuals or gametes, which tends to reduce genetic differences among populations.

Related: Genetic Drift, Natural Selection
Fitness

The relative contribution an individual makes to the gene pool of the next generation, often measured as reproductive success compared with other phenotypes in the population.

Related: Natural Selection, Genetic Drift
Transpiration

The loss of water vapor from plant surfaces, mainly through stomata in leaves, which drives upward water movement in the xylem and cools the plant.

Related: Xylem, Stomata
Xylem

Vascular tissue that conducts water and dissolved minerals upward from roots to shoots, composed of dead, lignified cells such as tracheids and vessel elements.

Related: Transpiration, Phloem
Phloem

Vascular tissue that transports sugars and other organic solutes from sources to sinks throughout the plant, using living sieve-tube elements supported by companion cells.

Related: Xylem, Transpiration
Stomata

Small pores in the leaf epidermis, each bounded by two guard cells, that regulate gas exchange and water loss by opening and closing.

Related: Transpiration, Phloem
Antibiotic Resistance

The ability of bacteria to survive and multiply in the presence of an antibiotic that would normally inhibit or kill them, often acquired through mutation or horizontal gene transfer.

Related: Horizontal Gene Transfer, Natural Selection
Horizontal Gene Transfer

The movement of genetic material between organisms other than by parent-to-offspring inheritance, occurring in bacteria through transformation, transduction, and conjugation.

Related: Antibiotic Resistance, Plasmid
Plasmid

A small, circular, extrachromosomal DNA molecule that replicates independently of the bacterial chromosome and often carries genes such as those for antibiotic resistance.

Related: Horizontal Gene Transfer, Antibiotic Resistance