CCI study materials
CCI study resources

CCI study guide

CCI · Work through your exam, one topic at a time.

The Certified Clinical Informatics (CCI) credential is aimed at clinicians and informatics professionals who design, configure, implement, and optimize health IT systems and want independent evidence of that competence. Candidates typically come from nursing, medicine, pharmacy, allied health, and health IT analyst or project roles, and share a working vocabulary of workflow analysis, EHR configuration, interoperability standards, and governance. The CCI study guide has 8 sections and about 2,217 words.

01

Clinical Informatics Fundamentals and Health IT Environment

This domain tests whether you can place clinical informatics in the wider health IT environment: core definitions, roles, the models that explain how data becomes action, and the systems and regulators that shape the EHR landscape. Questions often ask you to distinguish terms and select the right informatics lens rather than recall vendor products.

312 words, about 2 min
02

Clinical Workflow and Process Analysis

Clinical workflow and process analysis tests your ability to observe, map, analyze, and redesign care processes. Expect questions on current-state versus future-state mapping, appropriate artifacts, Lean and Six Sigma concepts, and how to measure whether a change actually reduced delay or rework.

282 words, about 1 min
03

Health Information Systems and Electronic Health Records

Health information systems and EHRs tests core EHR functions, architecture, interfaces, usability, downtime, and lifecycle. Questions ask you to connect a function to its safety purpose and to recognize where a system design choice creates new risk.

276 words, about 1 min
04

Data Management, Standards, and Interoperability

Data management, standards, and interoperability tests governance, data quality, terminology, and exchange standards. Expect questions that ask you to select the right standard for a use case, distinguish messaging from documents and APIs, and explain why semantic interoperability is harder than transport.

271 words, about 1 min
05

Clinical Decision Support and Knowledge Management

Clinical decision support and knowledge management tests how you design, deploy, and maintain CDS. Questions focus on the Five Rights, CDS types, governance, alert fatigue, and measurement, including when to revise or retire a rule.

277 words, about 1 min
06

Privacy, Security, and Regulatory Compliance

Privacy, security, and regulatory compliance tests HIPAA and related rules as they apply to health IT. Expect questions on permitted uses and disclosures, safeguards, breach assessment, patient rights, and special regimes such as 42 CFR Part 2.

287 words, about 1 min
07

Quality Improvement and Patient Safety

Quality improvement and patient safety tests the methods used to measure, analyze, and improve care and to build safer systems. Questions ask you to choose a framework, interpret variation, and avoid blame-oriented responses to error.

270 words, about 1 min
08

Leadership, Implementation, and Change Management

Leadership, implementation, and change management tests how informatics projects are governed, delivered, adopted, and sustained. Expect questions on charters, stakeholders, change models, go-live readiness, and benefits realization.

242 words, about 1 min