MTLE Life Science (Grades 9-12) key terms
MTLE Life Science (Grades 9-12) · Get comfortable with the vocabulary.
- Cell membrane
- Related: Diffusion and osmosis, Active transport
A phospholipid bilayer studded with proteins that surrounds every cell and controls which substances enter or leave, using selective permeability and transport proteins.
- Diffusion and osmosis
- Related: Cell membrane, Active transport
Passive movement of particles from high to low concentration; osmosis is the same process applied specifically to water crossing a semipermeable membrane. Neither requires cellular energy input.
- Active transport
- Related: Cell membrane, Diffusion and osmosis
Movement of substances against their concentration gradient through membrane proteins, powered by ATP, as in the sodium-potassium pump that maintains ion gradients in nerve cells.
- Enzyme
- Related: Denaturation, Metabolism
A protein catalyst that speeds a specific biochemical reaction by lowering activation energy; its shape determines substrate specificity and it is not consumed by the reaction.
- Denaturation
- Related: Enzyme
Loss of a protein's three-dimensional shape, and therefore its function, caused by heat, extreme pH, or heavy metals that disrupt hydrogen bonds and other weak interactions.
- Metabolism
- Related: Enzyme, Cellular respiration, Photosynthesis
The sum of all chemical reactions in a cell, split into catabolic pathways that break molecules down to release energy and anabolic pathways that build molecules using energy.
- Cellular respiration
- Related: Glycolysis, Fermentation, Metabolism
The oxygen-requiring breakdown of glucose through glycolysis, the Krebs cycle, and the electron transport chain to produce ATP, with carbon dioxide and water as waste products.
- Glycolysis
- Related: Cellular respiration, Fermentation
The first stage of respiration, occurring in the cytoplasm without oxygen, in which one glucose molecule is split into two pyruvate molecules with a net gain of two ATP.
- Fermentation
- Related: Glycolysis, Cellular respiration
An anaerobic pathway that regenerates NAD+ so glycolysis can continue, producing lactate in muscle cells or ethanol and carbon dioxide in yeast.
- Photosynthesis
- Related: Chloroplast, Cellular respiration
The light-driven process in chloroplasts that converts carbon dioxide and water into glucose and oxygen, coupling light reactions that make ATP and NADPH with the Calvin cycle.
- Chloroplast
- Related: Photosynthesis, Mitochondrion
A plant cell organelle containing thylakoid membranes and the pigment chlorophyll, where light energy is captured and converted into chemical energy during photosynthesis.
- Mitochondrion
- Related: Cellular respiration, Chloroplast
A double-membraned organelle whose inner membrane hosts the electron transport chain, generating most of a eukaryotic cell's ATP through aerobic respiration.
- Mitosis
- Related: Meiosis, Cell cycle
Nuclear division producing two genetically identical daughter cells, used for growth and repair; it includes prophase, metaphase, anaphase, and telophase followed by cytokinesis.
- Meiosis
- Related: Mitosis, Crossing over, Independent assortment
Two successive nuclear divisions that halve chromosome number and create four genetically varied gametes through crossing over and independent assortment of homologous chromosomes.
- Cell cycle
- Related: Mitosis, Mutation
The ordered sequence of interphase growth and DNA synthesis followed by mitotic division, tightly regulated at checkpoints so damaged DNA is not copied or passed on.
- DNA replication
- Related: Mutation, Central dogma
Semiconservative copying of the double helix, in which helicase unwinds DNA and polymerase builds complementary strands so each new molecule keeps one original strand.
- Central dogma
- Related: Transcription and translation, DNA replication
The flow of genetic information from DNA to RNA to protein: transcription makes messenger RNA, and translation at the ribosome assembles amino acids in the order the codons specify.
- Transcription and translation
- Related: Central dogma, Codon
Transcription copies a gene into mRNA in the nucleus; translation reads mRNA codons at ribosomes, matching each to transfer RNA carrying a specific amino acid.
- Codon
- Related: Transcription and translation, Mutation
A sequence of three mRNA bases that specifies one amino acid or a stop signal; the genetic code is nearly universal and redundant, with several codons per amino acid.
- Mutation
- Related: DNA replication, Codon
A heritable change in DNA sequence, such as substitution, insertion, or deletion; effects range from silent to harmful, and frameshifts usually alter every downstream codon.
- Mendelian inheritance
- Related: Punnett square, Independent assortment, Genotype and phenotype
Patterns described by Mendel in which alleles segregate and assort independently, producing predictable ratios such as 3:1 from a monohybrid cross of heterozygotes.
- Punnett square
- Related: Mendelian inheritance, Genotype and phenotype
A grid used to predict offspring genotype ratios by combining the possible gametes of two parents, given each parent's genotype at the locus in question.
- Genotype and phenotype
- Related: Mendelian inheritance, Punnett square
Genotype is an organism's allele combination at a locus; phenotype is the observable trait produced by that genotype interacting with the environment.
- Crossing over
- Related: Meiosis, Independent assortment
Exchange of chromosome segments between homologous partners during prophase I of meiosis, which reshuffles alleles and increases genetic variation in gametes.
- Independent assortment
- Related: Meiosis, Crossing over, Mendelian inheritance
The random orientation of homologous chromosome pairs at meiosis I, so alleles of genes on different chromosomes are inherited independently of one another.
- Natural selection
- Related: Allele frequency, Speciation, Adaptation
Differential survival and reproduction of individuals whose inherited traits suit their environment, causing allele frequencies in a population to shift over generations.
- Allele frequency
- Related: Natural selection, Hardy-Weinberg equilibrium
The proportion of a population's gene copies represented by a particular allele; changes in these frequencies across generations define evolutionary change.
- Hardy-Weinberg equilibrium
- Related: Allele frequency, Natural selection
A null model in which allele and genotype frequencies stay constant absent mutation, migration, selection, genetic drift, and nonrandom mating; deviations signal evolution.
- Speciation
- Related: Natural selection, Adaptation
The formation of new species, usually when gene flow stops between populations; geographic isolation (allopatric) or reproductive isolation in place (sympatric) allows divergence.
- Adaptation
- Related: Natural selection, Speciation
An inherited feature that improves fitness in a particular environment, produced by natural selection over generations rather than acquired during an individual's lifetime.
- Homeostasis
- Related: Feedback loop, Osmoregulation
Maintenance of stable internal conditions such as temperature and blood glucose through negative feedback loops that detect deviation and trigger corrective responses.
- Feedback loop
- Related: Homeostasis, Osmoregulation
A regulatory circuit in which a sensor detects a change and an effector counteracts it (negative feedback) or amplifies it (positive feedback, as in childbirth).
- Osmoregulation
- Related: Homeostasis, Feedback loop
Control of water and solute balance across membranes, achieved in kidneys by filtration, reabsorption, and secretion so body fluids stay within tolerable concentration ranges.
- Trophic level
- Related: Food web, Energy pyramid
A feeding position in a food web, such as producer, primary consumer, or secondary consumer; only about ten percent of energy passes to the next level.
- Food web
- Related: Trophic level, Energy pyramid
A network of interconnected feeding relationships among organisms in a community, showing how energy and matter move from producers through consumers to decomposers.
- Energy pyramid
- Related: Trophic level, Food web
A diagram showing energy lost at each trophic level; because most energy is used in metabolism or lost as heat, higher levels support far less biomass.
- Carrying capacity
- Related: Population growth, Limiting factor
The maximum population size an environment can sustain indefinitely given available food, water, space, and other limiting resources; growth slows as it is approached.
- Limiting factor
- Related: Carrying capacity, Population growth
Any resource or condition, such as nutrients, light, or predation, that restricts population growth or distribution when it is in shortest supply.
- Population growth
- Related: Carrying capacity, Limiting factor
Change in population size over time; exponential growth occurs with unlimited resources, while logistic growth levels off at carrying capacity as density-dependent factors intensify.
- Symbiosis
- Related: Food web, Carrying capacity
A close, lasting relationship between species, classified as mutualism (both benefit), commensalism (one benefits), or parasitism (one benefits at the other's expense).
- Scientific method
- Related: Hypothesis, Control group, Variable
An iterative cycle of observation, hypothesis formation, controlled experimentation, data analysis, and revision, in which hypotheses must be testable and potentially falsifiable.
- Hypothesis
- Related: Scientific method, Control group
A testable, falsifiable proposed explanation for an observation, stated so that predictions can be checked against evidence rather than accepted on authority.
- Variable
- Related: Control group, Scientific method
Any factor in an experiment that can change; a valid design manipulates one independent variable while holding others constant to isolate its effect.
- Control group
- Related: Variable, Hypothesis
The comparison group in an experiment that does not receive the treatment, establishing a baseline against which the experimental group's results are measured.
- Formative assessment
- Related: Summative assessment, Inquiry-based instruction
Ongoing, low-stakes checks on student understanding during instruction, used to adjust teaching in real time rather than to assign a final grade.
- Summative assessment
- Related: Formative assessment, Rubric
An evaluation of learning at the end of a unit or course, such as a test or lab practical, used to judge achievement against standards and report results.
- Inquiry-based instruction
- Related: Scientific method, Formative assessment
Teaching in which students investigate questions, design procedures, and construct explanations from evidence, with the teacher guiding rather than simply presenting facts.
- Rubric
- Related: Summative assessment
A scoring guide listing criteria and performance levels, giving students transparent expectations and making grading of lab reports and projects more consistent.
- Differentiation
- Related: Formative assessment, Inquiry-based instruction
Adjusting content, process, or product to meet varied readiness levels, interests, and learning profiles so all students can access the same learning goals.
- Laboratory safety
- Related: Personal protective equipment, Material Safety Data Sheet
Practices that prevent injury in science classrooms: goggles and gloves, chemical labeling and storage, eyewash and shower access, and supervised handling of specimens and equipment.
- Personal protective equipment
- Related: Laboratory safety, Material Safety Data Sheet
Barriers such as splash goggles, lab coats, and nitrile gloves worn to shield skin, eyes, and clothing from chemicals, heat, and biological material during laboratory work.
- Material Safety Data Sheet
- Related: Laboratory safety, Personal protective equipment
A document supplied with each hazardous chemical that lists its hazards, safe handling, storage, spill response, and first-aid measures for teachers and students.