MTLE Life Science (Grades 9-12) study plan
MTLE Life Science (Grades 9-12) · Give each week a clear focus.
8 weeks · About 6 hours per week
Cellular and Molecular Biology
Build a concept map linking the four macromolecule classes to their monomers, bonds, and cellular functions, reciting each from memory by week's end.
Diagram the endomembrane system and label the path a secreted protein takes from ribosome to extracellular space.
Compare prokaryotic and eukaryotic cell structures in a side-by-side table covering at least eight features.
Explain how the hydrophobic core of the plasma membrane constrains the movement of ions and polar molecules, using the terms diffusion, osmosis, and facilitated transport.
Your checkpoint
A hand-drawn or digital concept map of cell structure and macromolecules, plus a one-page written explanation of membrane transport checked against a textbook for accuracy.
Cellular and Molecular Biology
Trace the inputs and outputs of glycolysis, the Krebs cycle, and oxidative phosphorylation, stating where each occurs in the cell.
Calculate the net ATP yield per glucose molecule under aerobic versus anaerobic conditions and identify where the accounting differs.
Describe how enzymes lower activation energy and predict the effect of temperature, pH, and a competitive inhibitor on reaction rate.
Contrast photosynthesis and cellular respiration in terms of electron carriers, proton gradients, and energy flow.
Your checkpoint
A completed worksheet of 15 self-written questions on bioenergetics with worked answers, including two quantitative ATP-yield problems.
Cellular and Molecular Biology & Genetics and Evolution
Sequence the stages of mitosis and meiosis and state the chromosome and DNA content at each checkpoint.
Explain how crossing over and independent assortment generate genetic variation in gametes.
Describe the central dogma and distinguish transcription from translation in terms of location, template, and product.
Predict the phenotypic consequence of a specified point mutation (silent, missense, nonsense, frameshift) in a coding sequence.
Your checkpoint
A one-page flowchart from DNA to protein with mutation examples annotated, plus a meiosis-versus-mitosis comparison table.
Genetics and Evolution
Solve monohybrid and dihybrid crosses using Punnett squares and verify ratios with the product rule.
Distinguish complete dominance, incomplete dominance, codominance, and sex-linked inheritance using worked examples.
Interpret a pedigree to determine the most likely mode of inheritance and justify the reasoning.
Apply Hardy-Weinberg equations to calculate allele and genotype frequencies and identify which assumptions a given scenario violates.
Your checkpoint
A problem set of 20 genetics problems (at least five pedigrees and five Hardy-Weinberg calculations) solved with shown work, scored at 85 percent or higher.
Genetics and Evolution
Summarize the evidence for evolution from fossils, comparative anatomy, molecular homology, and biogeography.
Explain natural selection as a mechanism by distinguishing it from genetic drift, gene flow, and mutation.
Describe speciation pathways (allopatric, sympatric) and the role of reproductive isolating mechanisms.
Construct a cladogram from a small character matrix and interpret shared derived traits.
Your checkpoint
A written response of roughly 400 words arguing how a specified population could diverge into two species, citing at least three lines of evidence.
Organismal Biology and Ecology
Compare plant and animal organ systems in terms of transport, gas exchange, and waste removal.
Explain how homeostasis is maintained through negative feedback, using at least two physiological examples with sensors and effectors identified.
Analyze energy flow and trophic levels in a food web, calculating the approximate energy transferred between levels.
Describe population growth models (exponential, logistic) and the factors that produce carrying capacity.
Predict how removing a keystone species alters community structure and species richness.
Your checkpoint
A food-web diagram for a named ecosystem with trophic levels labeled and a paragraph predicting the effects of removing one keystone species.
Organismal Biology and Ecology & Scientific Inquiry, Pedagogy, and Laboratory Safety
Design a controlled experiment on a life science question, specifying independent, dependent, and controlled variables plus a negative control.
Evaluate a described experimental setup for sources of bias, confounding variables, and adequacy of sample size.
Interpret data presented as a table or graph, identifying trends and stating whether the data support the proposed hypothesis.
Write a laboratory safety plan covering chemical handling, biohazard disposal, and emergency procedures for a high school classroom.
Your checkpoint
A complete experimental design document for one investigation, including variables, procedure, safety plan, and a data table template.
Scientific Inquiry, Pedagogy, and Laboratory Safety & Cellular and Molecular Biology & Genetics and Evolution & Organismal Biology and Ecology
Construct a standards-aligned lesson outline for one life science topic that includes a phenomenon, an investigation, and an assessment check.
Create a rubric that scores scientific explanation using claim, evidence, and reasoning.
Complete a timed 60-question mixed practice test across all four domains and log every missed item by domain.
Re-teach your three weakest concepts from the practice test in short written summaries without notes.
Your checkpoint
A full practice-test score report with a domain-by-domain error log and three written re-teach summaries.
Milestones
Week 2: Explain cellular respiration and membrane transport aloud for five minutes without notes, and score at least 80 percent on a self-made 15-question bioenergetics quiz.
Week 4: Complete the 20-problem genetics set at 85 percent or higher, with pedigree and Hardy-Weinberg items all correct or corrected in writing.
Week 6: Draw a food web from memory, label trophic levels, and explain negative feedback with two physiological examples in under ten minutes.
Week 8: Score at least 75 percent on the mixed 60-question practice test with no single domain below 65 percent, and show the completed error log.