Russia Primary Medical Accreditation - General Medicine study materials
Russia Primary Medical Accreditation - General Medicine study resources

Russia Primary Medical Accreditation - General Medicine flashcards

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CURB-65 score
Pneumonia severity tool scoring confusion, urea >7 mmol/L, respiratory rate ≥30/min, low systolic or diastolic pressure, and age ≥65; 0–1 supports outpatient care.
qSOFA criteria
Bedside sepsis screen: respiratory rate ≥22/min, altered mentation, and systolic blood pressure ≤100 mmHg; two or more criteria indicate high risk of poor outcome.
Anion gap formula
Anion gap equals sodium minus the sum of chloride and bicarbonate, normally 8–12 mmol/L; an elevated gap suggests ketoacidosis, lactic acidosis, renal failure, or toxin ingestion.
KDIGO acute kidney injury
AKI is a creatinine rise of at least 26.5 µmol/L within 48 hours, at least 1.5 times baseline within 7 days, or urine output below 0.5 mL/kg/h for 6 hours.
CHA2DS2-VASc score
Stroke risk score in atrial fibrillation; anticoagulation is generally recommended at ≥2 in men and ≥3 in women, weighing bleeding risk with HAS-BLED.
Heart failure four pillars
For reduced ejection fraction: ACE inhibitor, ARB, or ARNI; beta-blocker; mineralocorticoid receptor antagonist; and SGLT2 inhibitor, each shown to reduce mortality.
Light's criteria
Pleural fluid is an exudate if protein ratio >0.5, LDH ratio >0.6, or pleural LDH exceeds two-thirds the upper normal serum LDH; otherwise it is a transudate.
GOLD airflow limitation
COPD is confirmed by a post-bronchodilator FEV1/FVC ratio below 0.70; severity grading and exacerbation history guide inhaled therapy selection.
Serum-ascites albumin gradient
A gradient of 11 g/L or more between serum and ascitic albumin indicates portal hypertension, most often cirrhosis; lower values suggest peritoneal malignancy or tuberculosis.
Spontaneous bacterial peritonitis
Diagnosed when ascitic fluid polymorphonuclear cells reach 250/mm³ or more; treat with a third-generation cephalosporin and intravenous albumin.
Diabetic ketoacidosis management
Isotonic saline resuscitation, insulin infusion at 0.1 U/kg/h, and potassium replacement once potassium is below 5.5 mmol/L with adequate urine output.
Adrenal crisis treatment
In hypotension with hyponatremia, hyperkalemia, or hypoglycemia, draw cortisol and ACTH then give intravenous hydrocortisone 100 mg immediately without waiting for results.
Heparin-induced thrombocytopenia
A platelet fall exceeding 50% at 5–10 days after heparin, causing thrombosis rather than bleeding; stop heparin and start a non-heparin anticoagulant.
Multiple myeloma CRAB features
Hypercalcemia, renal insufficiency, anemia, and bone lesions define symptomatic myeloma; serum protein electrophoresis and free light chains support diagnosis.
Gout crystal identification
Negatively birefringent needle-shaped monosodium urate crystals in synovial fluid confirm gout; calcium pyrophosphate crystals are positively birefringent and rhomboid.
Giant cell arteritis
Age over 50 with headache, jaw claudication, and elevated ESR; give high-dose glucocorticoids immediately and confirm with temporal artery biopsy.
Tuberculosis standard regimen
Two months of isoniazid, rifampicin, pyrazinamide, and ethambutol followed by four months of isoniazid and rifampicin for drug-susceptible pulmonary disease.
Sepsis one-hour bundle
Measure lactate, obtain blood cultures, give broad-spectrum antibiotics, begin 30 mL/kg crystalloid for hypotension or lactate ≥4, and start vasopressors if needed.
High-quality chest compressions
Compress at 100–120 per minute to a depth of 5–6 cm, allow full chest recoil, minimize interruptions, and change compressor every two minutes.
Anaphylaxis first-line treatment
Intramuscular adrenaline 0.5 mg of 1 mg/mL solution into the anterolateral thigh, repeated every five minutes as needed, with fluids for hypotension.
Screening levels of prevention
Primary prevention reduces risk before disease, secondary prevention detects disease early, and tertiary prevention limits disability and complications after disease onset.
Hypertension diagnosis confirmation
Diagnose hypertension only after repeated elevated office readings, confirmed by home or ambulatory blood pressure monitoring to exclude white-coat elevation.
Primary care gatekeeping
First-contact, continuous, comprehensive, and coordinated care in which the primary physician manages referrals and coordinates specialist and hospital services.
Chronic disease register
A structured list of patients with a long-term condition used for planned reviews, recall, and multidisciplinary management to reduce avoidable hospital admissions.
Cardiac rehabilitation components
Exercise training, risk-factor modification, education, and psychosocial support after myocardial infarction or revascularization; it reduces mortality and improves function.
Barthel index
A scored assessment of activities of daily living such as feeding, bathing, mobility, and continence, used to track rehabilitation progress and dependency.
Drug half-life steady state
Steady-state plasma concentration is reached after about four to five half-lives; half-life also determines dosing interval and duration after stopping therapy.
CYP450 enzyme inhibition
Macrolides, azole antifungals, and grapefruit inhibit cytochrome P450 enzymes and raise concentrations of co-administered drugs, increasing toxicity risk.
ECG interpretation sequence
Assess rate, rhythm, axis, PR/QRS/QT intervals, hypertrophy, and ischemia or infarction, then compare with previous tracings before concluding.
Arterial blood gas analysis
Interpret pH, PaCO2, PaO2, and bicarbonate to classify respiratory or metabolic acidosis and alkalosis, then calculate the anion gap for metabolic acidosis.
Informed consent elements
Valid consent requires patient capacity, adequate disclosure of risks, benefits, and alternatives, and a voluntary decision, documented in the medical record.
Medical confidentiality exceptions
Confidentiality may be breached with patient consent or where law mandates notification, such as certain infectious diseases and gunshot wounds.