Russia Primary Medical Accreditation - General Medicine flashcards
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- CURB-65 score
- Pneumonia severity tool scoring confusion, urea >7 mmol/L, respiratory rate ≥30/min, low systolic or diastolic pressure, and age ≥65; 0–1 supports outpatient care.
- qSOFA criteria
- Bedside sepsis screen: respiratory rate ≥22/min, altered mentation, and systolic blood pressure ≤100 mmHg; two or more criteria indicate high risk of poor outcome.
- Anion gap formula
- Anion gap equals sodium minus the sum of chloride and bicarbonate, normally 8–12 mmol/L; an elevated gap suggests ketoacidosis, lactic acidosis, renal failure, or toxin ingestion.
- KDIGO acute kidney injury
- AKI is a creatinine rise of at least 26.5 µmol/L within 48 hours, at least 1.5 times baseline within 7 days, or urine output below 0.5 mL/kg/h for 6 hours.
- CHA2DS2-VASc score
- Stroke risk score in atrial fibrillation; anticoagulation is generally recommended at ≥2 in men and ≥3 in women, weighing bleeding risk with HAS-BLED.
- Heart failure four pillars
- For reduced ejection fraction: ACE inhibitor, ARB, or ARNI; beta-blocker; mineralocorticoid receptor antagonist; and SGLT2 inhibitor, each shown to reduce mortality.
- Light's criteria
- Pleural fluid is an exudate if protein ratio >0.5, LDH ratio >0.6, or pleural LDH exceeds two-thirds the upper normal serum LDH; otherwise it is a transudate.
- GOLD airflow limitation
- COPD is confirmed by a post-bronchodilator FEV1/FVC ratio below 0.70; severity grading and exacerbation history guide inhaled therapy selection.
- Serum-ascites albumin gradient
- A gradient of 11 g/L or more between serum and ascitic albumin indicates portal hypertension, most often cirrhosis; lower values suggest peritoneal malignancy or tuberculosis.
- Spontaneous bacterial peritonitis
- Diagnosed when ascitic fluid polymorphonuclear cells reach 250/mm³ or more; treat with a third-generation cephalosporin and intravenous albumin.
- Diabetic ketoacidosis management
- Isotonic saline resuscitation, insulin infusion at 0.1 U/kg/h, and potassium replacement once potassium is below 5.5 mmol/L with adequate urine output.
- Adrenal crisis treatment
- In hypotension with hyponatremia, hyperkalemia, or hypoglycemia, draw cortisol and ACTH then give intravenous hydrocortisone 100 mg immediately without waiting for results.
- Heparin-induced thrombocytopenia
- A platelet fall exceeding 50% at 5–10 days after heparin, causing thrombosis rather than bleeding; stop heparin and start a non-heparin anticoagulant.
- Multiple myeloma CRAB features
- Hypercalcemia, renal insufficiency, anemia, and bone lesions define symptomatic myeloma; serum protein electrophoresis and free light chains support diagnosis.
- Gout crystal identification
- Negatively birefringent needle-shaped monosodium urate crystals in synovial fluid confirm gout; calcium pyrophosphate crystals are positively birefringent and rhomboid.
- Giant cell arteritis
- Age over 50 with headache, jaw claudication, and elevated ESR; give high-dose glucocorticoids immediately and confirm with temporal artery biopsy.
- Tuberculosis standard regimen
- Two months of isoniazid, rifampicin, pyrazinamide, and ethambutol followed by four months of isoniazid and rifampicin for drug-susceptible pulmonary disease.
- Sepsis one-hour bundle
- Measure lactate, obtain blood cultures, give broad-spectrum antibiotics, begin 30 mL/kg crystalloid for hypotension or lactate ≥4, and start vasopressors if needed.
- High-quality chest compressions
- Compress at 100–120 per minute to a depth of 5–6 cm, allow full chest recoil, minimize interruptions, and change compressor every two minutes.
- Anaphylaxis first-line treatment
- Intramuscular adrenaline 0.5 mg of 1 mg/mL solution into the anterolateral thigh, repeated every five minutes as needed, with fluids for hypotension.
- Screening levels of prevention
- Primary prevention reduces risk before disease, secondary prevention detects disease early, and tertiary prevention limits disability and complications after disease onset.
- Hypertension diagnosis confirmation
- Diagnose hypertension only after repeated elevated office readings, confirmed by home or ambulatory blood pressure monitoring to exclude white-coat elevation.
- Primary care gatekeeping
- First-contact, continuous, comprehensive, and coordinated care in which the primary physician manages referrals and coordinates specialist and hospital services.
- Chronic disease register
- A structured list of patients with a long-term condition used for planned reviews, recall, and multidisciplinary management to reduce avoidable hospital admissions.
- Cardiac rehabilitation components
- Exercise training, risk-factor modification, education, and psychosocial support after myocardial infarction or revascularization; it reduces mortality and improves function.
- Barthel index
- A scored assessment of activities of daily living such as feeding, bathing, mobility, and continence, used to track rehabilitation progress and dependency.
- Drug half-life steady state
- Steady-state plasma concentration is reached after about four to five half-lives; half-life also determines dosing interval and duration after stopping therapy.
- CYP450 enzyme inhibition
- Macrolides, azole antifungals, and grapefruit inhibit cytochrome P450 enzymes and raise concentrations of co-administered drugs, increasing toxicity risk.
- ECG interpretation sequence
- Assess rate, rhythm, axis, PR/QRS/QT intervals, hypertrophy, and ischemia or infarction, then compare with previous tracings before concluding.
- Arterial blood gas analysis
- Interpret pH, PaCO2, PaO2, and bicarbonate to classify respiratory or metabolic acidosis and alkalosis, then calculate the anion gap for metabolic acidosis.
- Informed consent elements
- Valid consent requires patient capacity, adequate disclosure of risks, benefits, and alternatives, and a voluntary decision, documented in the medical record.
- Medical confidentiality exceptions
- Confidentiality may be breached with patient consent or where law mandates notification, such as certain infectious diseases and gunshot wounds.