AANPCB A-GNP study materials
AANPCB A-GNP study resources

AANPCB A-GNP key terms

AANPCB A-GNP · Get comfortable with the vocabulary.

Screening test

A test given to people who have no symptoms of a disease, aiming to find it early when treatment works better. It should have proven benefit and acceptable harms before being offered routinely.

Related: USPSTF grade, Sensitivity
USPSTF grade

A letter grade from A to D, or I for insufficient evidence, that the U.S. Preventive Services Task Force assigns to a preventive service based on strength of evidence and balance of benefits and harms.

Related: Screening test, Number needed to treat
Number needed to treat

The number of patients who must receive an intervention for one additional person to gain the intended benefit. Smaller values mean a stronger treatment effect and help weigh prevention choices.

Related: USPSTF grade, Shared decision-making
Shared decision-making

A conversation in which the clinician explains options and evidence while the patient shares values and preferences, and together they agree on a plan of care.

Related: Motivational interviewing, Number needed to treat
Motivational interviewing

A patient-centered counseling style that draws out and strengthens a person's own reasons for changing a behavior, using open questions, affirmations, reflections, and summaries while respecting autonomy.

Related: Shared decision-making
Teach-back

A checking technique in which the patient restates the plan or instructions in their own words, so the clinician can correct misunderstandings before the patient leaves.

Related: Shared decision-making, Motivational interviewing
Community immunity

Indirect protection that appears when enough people in a group are immune to an infection, which slows transmission and shields those who cannot be vaccinated.

Related: Adult immunization schedule
Adult immunization schedule

Annually updated recommendations for which vaccines adults need, and when, adjusted for age, pregnancy, occupation, chronic disease, and immune status.

Related: Community immunity
ASCVD 10-year risk estimate

A calculation using age, sex, blood pressure, cholesterol, smoking, and diabetes to estimate the chance of a heart attack or stroke in the next ten years.

Related: Shared decision-making, Number needed to treat
Sensitivity

The share of people who truly have a disease and whose test is correctly positive. A very sensitive test is most useful for ruling out disease when the result is negative.

Related: Specificity, Likelihood ratio
Specificity

The share of people without the disease whose test is correctly negative. A very specific test is most useful for ruling in disease when the result is positive.

Related: Sensitivity, Positive predictive value
Positive predictive value

The chance that a patient with a positive result really has the disease. It depends on specificity and on how common the disease is in the population tested.

Related: Specificity, Pretest probability
Pretest probability

The estimated chance that a patient has a condition before testing, based on history, examination, and local prevalence. It determines whether a test result will meaningfully change management.

Related: Likelihood ratio, Positive predictive value
Likelihood ratio

A number showing how much a given test result multiplies the odds of disease. Values far from 1.0 shift thinking substantially; values near 1.0 change very little.

Related: Pretest probability, Sensitivity
Differential diagnosis

An ordered list of possible explanations for a patient's problem, ranked by how likely each is and by how harmful it would be to miss it.

Related: Red flag, Pretest probability
Red flag

A symptom, sign, or history detail that suggests a dangerous cause and calls for urgent evaluation instead of routine or watchful management.

Related: Differential diagnosis
Community-acquired pneumonia

Acute infection of lung tissue acquired outside a hospital, recognized by fever, cough, dyspnea, and a new infiltrate, with empiric antibiotics chosen by severity and comorbidity.

Related: CURB-65, Antibiotic stewardship
CURB-65

A five-item score - confusion, urea, respiratory rate, blood pressure, and age 65 or older - that estimates pneumonia mortality and helps decide whether to admit the patient.

Related: Community-acquired pneumonia
McIsaac score

A point system using fever, absence of cough, tonsillar exudate, and tender anterior neck nodes to estimate the probability of streptococcal pharyngitis and guide testing decisions.

Related: Antibiotic stewardship
Antibiotic stewardship

Organized efforts to prescribe antibiotics only when bacterial infection is likely, at the right drug, dose, and duration, to limit resistance and adverse effects.

Related: McIsaac score, Uncomplicated cystitis
Uncomplicated cystitis

Bladder infection in a nonpregnant woman with a normal urinary tract and no systemic illness, usually managed with a short course of oral antibiotics.

Related: Antibiotic stewardship
Hypertensive emergency

Markedly elevated blood pressure with acute target-organ damage such as encephalopathy, pulmonary edema, or aortic dissection, requiring monitored intravenous lowering in a hospital setting.

Related: Red flag
Individualized A1c goal

A glycated hemoglobin target tailored to the patient, often below 7% for many nonpregnant adults and higher for those with hypoglycemia risk, frailty, or limited life expectancy.

Related: Shared decision-making, Frailty
CKD staging

Classification of chronic kidney disease using both a glomerular filtration rate category and an albuminuria category, because the pair predicts progression better than either measure alone.

Heart failure with reduced ejection fraction (HFrEF)

Heart failure with left ventricular ejection fraction of 40% or less, treated with combined neurohormonal blockade and other guideline-directed drugs that improve survival.

Related: NYHA class
NYHA class

A four-step scale describing how much ordinary activity provokes heart failure symptoms, used to grade severity and track response to therapy over time.

Related: Heart failure with reduced ejection fraction (HFrEF)
Post-bronchodilator FEV1/FVC ratio

The ratio of forced expiratory volume in one second to forced vital capacity measured after a bronchodilator; a value below 0.70 supports persistent airflow obstruction and chronic obstructive pulmonary disease.

Polypharmacy

Use of many medications at once, commonly five or more, which raises the chance of interactions, adverse effects, and nonadherence and should prompt regular review.

Related: Beers criteria, Deprescribing
Beers criteria

A regularly updated list of medications considered potentially inappropriate for older adults because their risks often outweigh benefits, used to guide safer prescribing.

Related: Polypharmacy, Deprescribing
Deprescribing

The planned, supervised tapering or stopping of medicines that no longer help or whose harms exceed benefits, done with monitoring and the patient's agreement.

Related: Polypharmacy, Beers criteria
Delirium

An acute, fluctuating disturbance of attention and awareness caused by illness, drugs, pain, or withdrawal. It signals serious underlying disease and is not a normal part of aging.

Related: Dementia, Beers criteria
Dementia

A chronic, progressive decline in memory or other thinking skills severe enough to interfere with daily function, with an insidious course unlike the sudden onset of delirium.

Related: Delirium
Falls risk assessment

A structured review of gait, balance, strength, vision, footwear, medications, and home hazards for older adults, often starting with a timed up-and-go test.

Related: Frailty, Polypharmacy
Frailty

A state of lowered physiologic reserve that makes a person vulnerable to small stressors, suggested by unintentional weight loss, exhaustion, weakness, slow walking, and low activity.

Related: Falls risk assessment, Delirium
Advance care planning

Ongoing conversations and written documents that record a person's goals, values, chosen health care proxy, and treatment preferences for a time when they cannot speak for themselves.

Related: Shared decision-making
Urinary incontinence patterns

Types of involuntary urine loss: stress with coughing or lifting, urgency with sudden bladder contractions, overflow with retention, and functional when toileting barriers exist.

Related: Polypharmacy