ABR TMP study materials
ABR TMP study resources

ABR TMP cheat sheet

ABR TMP · Keep the key ideas within reach.

Quick reference

Treatment Planning and Dosimetry

  • TG-51 absorbed-dose-to-water formalism: D_w^Q = M · N_D,w^60Co · k_Q · P_Q, where P_Q = P_ion · P_TP · P_pol · P_elec; photon reference geometry is 10 × 10 cm² at 100 cm SSD with the reference depth near 10 cm for 6 MV.

  • TMR(d, FS) is defined at fixed SAD and is independent of SSD; PDD depends on both SSD and field size, and TMR = (PDD/100) · [(SSD + d_max)/(SSD + d)]².

  • Mayneord F factor for changing SSD: F = [(SSD₂ + d_max)/(SSD₁ + d_max)]² × [(SSD₁ + d)/(SSD₂ + d)]²; PDD₂ = PDD₁ × F.

  • Equivalent square field for collimator scatter: side = 4A/P (four times area divided by perimeter); square-field output and depth-dose data are then used for rectangular fields.

  • Fractionation: BED = n·d·(1 + d/(α/β)); EQD2 = BED/(1 + 2/(α/β)); α/β is about 10 Gy for tumor and 3 Gy for late-responding normal tissue.

  • Convolution-superposition computes TERMA from primary fluence and deposits it with a dose-spread kernel; pencil-beam algorithms lose accuracy in lung, bone, and small fields where lateral electronic disequilibrium dominates.

  • Gamma index combines dose-difference and distance-to-agreement criteria; typical IMRT/VMAT patient-specific QA is 3%/3 mm with a 10% dose threshold and a passing rate above 95% of evaluated points.

  • Plan metrics: Paddick conformity index = (TV_PIV)²/(TV × PIV); ICRU-83 homogeneity index = (D2 − D98)/D50; gradient index = volume of half the prescription isodose divided by PIV.

  • Electron beam energy from depth-dose: E₀ (MeV) ≈ 2.33 × R50 (cm); therapeutic range R90 ≈ E₀/4 in centimeters of water, and surface dose rises with increasing energy.

Quick reference

Treatment Delivery, Machine Calibration, and Quality Assurance

  • TG-142 output tolerances relative to baseline: daily constancy ±3%, monthly calibration ±2%, annual calibration ±1% for both photons and electrons.

  • Reference chamber correction: P_TP = [(273.15 + T)/295.15] × (760/P), with T in degrees Celsius and P in mm Hg; reference conditions are 22 °C and 760 mm Hg.

  • Ion recombination correction P_ion is obtained by the two-voltage method: measure charge at the normal bias and at half bias, take the ratio, and apply the standard TG-51 quadratic solution.

  • Radiation and mechanical isocenter coincidence is verified with the Winston-Lutz test (marker plus small field over multiple gantry, collimator, and couch angles); tolerance is about 1 mm.

  • MLC tests: picket-fence imaging detects leaf position and calibration drift; IMRT leaf positioning accuracy tolerance is 1 mm, and the dosimetric leaf gap compensates for rounded leaf ends and transmission.

  • TG-142 energy constancy tolerance is ±2% for photons and ±3% for electrons, assessed from the ratio of chamber readings at two depths in a fixed phantom.

  • Daily mechanical checks: lasers and ODI agree with isocenter to ±2 mm, gantry/collimator digital readouts to ±1°, and couch position to ±2 mm and ±1°.

  • VMAT and IMRT delivery verification uses machine log files or dynalog files to confirm gantry speed, dose rate, and MLC trajectory, plus an independent dose recalculation agreeing within 3%/3 mm.

  • End-to-end testing with an anthropomorphic phantom validates the full chain from imaging and contouring through planning, transfer, setup, and delivery, including heterogeneity and small-field effects.

Quick reference

Brachytherapy

  • TG-43 dose formalism: D(r,θ) = S_k · Λ · [G(r,θ)/G(r₀,θ₀)] · g(r) · F(r,θ), where Λ is the dose rate constant, g the radial dose function, and F the anisotropy function.

  • Air kerma strength units: 1 U = 1 μGy·m²/h = 1 cGy·cm²/h; source strength is measured in a well chamber calibrated against a traceable standard, with verification within ±3% of the vendor assay.

  • Common radionuclides and half-lives: Ir-192 = 73.8 days, I-125 = 59.4 days, Pd-103 = 17.0 days, Cs-131 = 9.7 days; Ir-192 photons average roughly 380 keV.

  • Gynecologic Point A is 2 cm lateral to the tandem and 2 cm superior to the external cervical os along the intrauterine applicator; ICRU 38 bladder and rectal reference points remain in use for reporting.

  • Combined EBRT plus image-guided brachytherapy targets (EQD2, α/β = 10 for tumor, 3 for organs at risk): HR-CTV D90 ≥ 85 Gy, bladder D2cc ≤ 90 Gy, rectum D2cc ≤ 70–75 Gy.

  • Permanent prostate implant dosimetry by TG-137: postimplant D90 of at least 100% of the prescribed dose and V100 of at least 95% are accepted adequacy benchmarks for monotherapy.

  • High-dose-rate daily QA: timer accuracy within ±1% for intervals over 1 second, source position within ±1 mm of intended location, functional emergency retraction, and a calibrated survey meter.

  • Emergency procedure for a stuck source: use long forceps and a shielded container, manually retract the source, monitor with a survey meter, and restrict access until the room is verified clear.

Quick reference

Imaging for Radiation Therapy and Simulation

  • CT simulation protocol: slice thickness of 2–3 mm through the target volume, scan extent sufficient for matching and dose calculation, flat couch top, indexed immobilization, and external isocenter markers.

  • Hounsfield units are converted to electron density by stoichiometric calibration using tissue-equivalent inserts; the density phantom is scanned annually and after major CT service.

  • Four-dimensional CT sorts images by respiratory phase or amplitude and defines the internal target volume; artifacts include blurring, duplication, and phase mismatch at irregular breathing.

  • Cone-beam CT has degraded Hounsfield accuracy from scatter and truncation, so it is used for setup and monitoring rather than primary dose calculation unless calibrated with a density phantom.

  • Magnetic resonance simulation requires assessment of geometric distortion from gradient nonlinearity and B0 inhomogeneity; AAPM TG-284 covers geometry, QA phantoms, and distortion correction.

  • PET/CT contributes metabolic target information; SUV depends on injected activity, uptake time, and reconstruction, and respiratory motion causes mismatch between PET and CT datasets.

  • DICOM radiotherapy objects: CT (image), RTSTRUCT (contours), RTPLAN (beams and MLC), RTDOSE (dose grid), RTIMAGE (portal/DRR images), and RTRECORD (delivered treatment).

  • Image-guided radiotherapy options include planar kV/kV imaging, CBCT, ultrasound, electromagnetic transponders, and surface imaging; each adds setup accuracy with a different dose and workflow cost.

Quick reference

Radiation Protection, Safety, Informatics, and Professionalism

  • NCRP Report 151 shielding: transmitted dose P = (W · U · T)/d² and barrier thickness = TVL · log₁₀(1/B), where B is the required attenuation factor for workload W, use factor U, occupancy T, and distance d.

  • Dose limits: occupational effective dose 50 mSv per year, public 1 mSv per year, and public-area ambient rate at or below 0.02 mSv per hour in any hour (NCRP), with ALARA applied below all limits.

  • Linear accelerator leakage must average no more than 0.1% and never exceed 0.2% of the useful beam dose rate; secondary barriers are designed for leakage plus patient-scattered radiation.

  • Primary barriers block the useful beam for workloads with the specified use factor (often 0.25 for walls and 1.0 for the floor in a four-field arrangement); secondary barriers account for leakage and scatter with use factor 1.

  • AAPM TG-100 applies failure mode and effects analysis prospectively: each step receives severity, occurrence, and detectability scores, and the risk priority number is their product, guiding mitigation priority.

  • AAPM TG-263 standardizes structure and plan nomenclature, while DICOM-RT, HL7, and IHE-RO profiles support interoperable exchange between planning, record-and-verify, and oncology information systems.

  • Incident learning is supported by RO-ILS and TG-100 methods; a facility radiation safety officer administers the radioactive materials license under 10 CFR Part 35 in NRC or Agreement State jurisdictions.

  • Radioactive sources and waste are held in storage until decay to background, conventionally estimated as ten half-lives; packages are surveyed and wipe-tested on receipt and before disposal.