ARRT Nuclear Medicine study materials
ARRT Nuclear Medicine study resources

ARRT Nuclear Medicine study plan

ARRT Nuclear Medicine · Give each week a clear focus.

8 weeks · About 6 hours per week

Week 1

Diagnostic Procedures / Clinical Applications

  • Map 15 core studies (bone scan, V/Q, myocardial perfusion, thyroid, renal, hepatobiliary, GI bleed, Meckel's, sentinel node, parathyroid, brain, lung shunt, gastric emptying, RBC, lymphoscintigraphy) to their radiopharmaceutical, adult dose range, patient preparation, and normal biodistribution.

  • Differentiate the clinical indications, contraindications, and typical findings for each mapped procedure.

  • Describe positioning, acquisition parameters (static, dynamic, whole-body, SPECT), and common technical artifacts for planar versus tomographic studies.

  • Explain how each study's result changes patient management for at least one representative pathology per study.

Your checkpoint

One-page protocol card for each of 15 studies, plus a score of 80% or higher on a 40-question Domain 1 self-quiz.

Week 2

Diagnostic Procedures / Clinical Applications & Radiopharmacy and Radiopharmaceuticals

  • Recall the radiopharmaceutical-to-procedure table closed-book to at least 90% accuracy.

  • Explain the mechanism of localization for each agent (chemisorption, phagocytosis, active transport, capillary blockade, antigen-antibody, compartmental distribution).

  • Calculate pediatric dose adjustments by weight and Clark's formula, and verify adult dose ranges against package insert values.

  • Compare the biodistribution, excretion pathway, and critical organ for the 10 highest-yield agents.

Your checkpoint

Closed-book 30-question mixed Domain 1/2 quiz scored at 85% or higher, plus a completed localization-mechanism comparison table.

Week 3

Radiopharmacy and Radiopharmaceuticals

  • Describe the Mo-99/Tc-99m generator system, elution process, and calculate eluate activity, concentration, and generator efficiency at a given time.

  • Perform pre-calibration and post-calibration decay calculations for Tc-99m, F-18, I-131, Ga-67, In-111, and Tl-201.

  • Evaluate radiopharmaceutical quality by describing radiochemical purity testing (paper and TLC), radionuclidic purity, aluminum breakthrough, and pH limits with their acceptance criteria.

  • Differentiate adverse reactions, drug interactions, and required patient preparation (thyroid blocking, fasting, medication holds) for common agents.

  • Outline aseptic technique, unit-dose handling, and record-keeping requirements for radiopharmacy operations.

Your checkpoint

20 timed calculation problems with fully worked solutions at 85% or higher accuracy, plus a completed generator elution and efficiency worksheet.

Week 4

Instrumentation and Image Production (including PET and CT)

  • Trace the signal path from scintillation crystal through PMT and pulse-height analyzer, and explain how energy window settings and peaking affect image quality.

  • Compare parallel-hole, pinhole, converging, diverging, and slant-hole collimators, and select the appropriate collimator for a given radionuclide energy and study.

  • Describe SPECT acquisition and reconstruction (filtered back projection versus iterative), attenuation correction methods, and PET detector, coincidence, and time-of-flight fundamentals.

  • Explain CT acquisition parameters and how CT data are used for attenuation correction and anatomic localization in SPECT/CT and PET/CT.

  • Identify uniformity, center-of-rotation, ring, motion, and truncation artifacts along with their cause and correction.

Your checkpoint

Annotated block diagram of the gamma camera and PET/CT signal chain, plus a 30-question Domain 3 quiz scored at 80% or higher.

Week 5

Instrumentation and Image Production (including PET and CT) & Radiation Safety and Protection

  • Calculate radiation exposure using the inverse square law, half-value layer, and time-distance-shielding principles.

  • Apply NRC and agreement-state dose limits for occupational workers, the public, declared pregnant workers, and breastfeeding patients.

  • Explain personnel and area monitoring with TLD/OSL badges, survey meters, wipe tests, and their action levels.

  • Describe spill response, decontamination procedures, and decay-in-storage radioactive waste handling.

  • Verify posting, labeling, and shielding requirements for restricted and unrestricted areas.

Your checkpoint

15-problem radiation safety calculation set with worked solutions, plus a completed spill-response checklist paired with a dose-limit reference table.

Week 6

Radiation Safety and Protection & Patient Care and Quality Control

  • Perform and interpret dose calibrator constancy, linearity, geometry, and accuracy tests and state the tolerance and frequency for each.

  • State the frequency, tolerance limit, and corrective action for gamma camera uniformity and resolution, well counter, survey meter, and PET daily QC tests.

  • Describe patient preparation, education, and contraindications for I-131, Sr-89, Ra-223, Y-90 microsphere, and other common therapies.

  • Explain infection control, extravasation management, and the care of pediatric, pregnant, and breastfeeding patients.

  • Apply ALARA-based workflow decisions to case scenarios involving staff, family, and public exposure.

Your checkpoint

Master QC table (test, frequency, tolerance limit, corrective action) plus a 25-question Domain 5 quiz scored at 85% or higher.

Week 7

Patient Care and Quality Control & Diagnostic Procedures / Clinical Applications & Radiopharmacy and Radiopharmaceuticals & Instrumentation and Image Production (including PET and CT) & Radiation Safety and Protection

  • Build an error log from every missed item in prior quizzes and rewrite each rationale in your own words.

  • Rehearse timed math drills covering decay, generator efficiency, pediatric dosing, attenuation, and exposure calculations.

  • Practice mixed question sets that interleave image interpretation, instrumentation, and radiopharmacy items.

  • Re-test the specific concepts that were missed most often until each reaches 85% mastery.

Your checkpoint

Error log with at least 40 corrected entries and a re-test score of 85% or higher on the previously missed concepts.

Week 8

Diagnostic Procedures / Clinical Applications & Radiopharmacy and Radiopharmaceuticals & Instrumentation and Image Production (including PET and CT) & Radiation Safety and Protection & Patient Care and Quality Control

  • Complete two timed full-length mock exams under test-like conditions.

  • Classify every miss as a knowledge gap, a misread stem, or a calculation slip, and remediate each category.

  • Recite high-yield flashcards on radiopharmaceuticals, dose limits, and QC tolerances without notes.

  • Finalize test-day logistics including scheduling, identification, arrival time, and a fatigue-management plan.

Your checkpoint

Two completed full-length mock exams scored at 80% or higher with a one-page high-yield summary sheet for final review.

Milestones

Week 2: Score 85% or higher on the closed-book 30-question Domain 1/2 quiz and complete the localization-mechanism table from memory.

Week 4: Score 75% or higher on a 100-question mid-point mock covering Domains 1-3, with no domain below 65%.

Week 6: Score 80% or higher on a 50-question mock covering Domains 4-5, and complete the master QC table with all tolerances correct.

Week 7: Score 75% or higher overall and 70% or higher in each of the five domains on a full-length 150-question mock.

Week 8: Score 80% or higher on both timed full-length mock exams, with all five domains at 75% or higher.