Fachapotheker/in FPH Spital study plan

List the core steps of medication reconciliation at admission, transfer, and discharge, and explain how each step reduces unintended discrepancies.

Compare the mechanisms, monitoring parameters, and key adverse effects of the main antibiotic classes used in hospital practice (beta-lactams, glycopeptides, aminoglycosides, fluoroquinolones).

Outline the components of a structured drug therapy review (indication, effectiveness, safety, adherence) and apply them to two common internal medicine scenarios (e.g., heart failure, COPD exacerbation).

Identify high-risk medications in hospitalized patients and describe at least three specific safety checks for each.

Explain the pathophysiology and first-line pharmacotherapy of acute coronary syndrome, heart failure, and atrial fibrillation, including dosing and monitoring in renal impairment.

Describe the principles of antimicrobial stewardship and apply them to choose empiric therapy for common infections (pneumonia, urinary tract infection, sepsis) based on local resistance patterns.

Calculate creatinine clearance using Cockcroft-Gault and adjust doses of at least five renally eliminated drugs accordingly.

Interpret therapeutic drug monitoring results for vancomycin and aminoglycosides, and recommend dose adjustments based on pharmacokinetic principles.

Summarize the mechanisms, monitoring, and management of immune-related adverse events for checkpoint inhibitors and of febrile neutropenia in oncology patients.

Describe the pharmacokinetic changes in critically ill patients (altered volume of distribution, augmented renal clearance) and adjust dosing of sedatives and antibiotics accordingly.

Explain age-related pharmacokinetic and pharmacodynamic changes and apply them to deprescribing decisions in geriatric patients (e.g., benzodiazepines, anticholinergics).

Classify medication errors by stage (prescribing, dispensing, administration) and propose one preventive strategy for each stage.

Outline the key requirements of GMP for hospital manufacturing, including cleanroom classification, environmental monitoring, and validation of sterile processes.

Describe the principles of non-sterile compounding (weighing, mixing, quality control) and the documentation required for a magistral preparation.

Explain the procurement process for hospital drugs, including tender procedures, safety stock calculation, and management of drug shortages.

Compare storage requirements for different drug classes (cold chain, narcotics, hazardous drugs) and describe the associated documentation and security measures.

Summarize the Swiss legal framework for hospital pharmacy practice: HMG, BetmVV, Swissmedic requirements for hospital exemptions, and narcotics regulations.

Explain the governance of a hospital formulary, including the role of the pharmacy and therapeutics committee and the criteria for drug inclusion.

Describe the design and operation of automated dispensing systems and their impact on medication safety and inventory control.

Outline the legal and practical requirements for handling narcotics in the hospital, from prescribing to destruction.

Explain the pharmacovigilance system in Switzerland, including reporting requirements for ADRs to Swissmedic and the role of the hospital pharmacist.

Apply pharmacokinetic principles to interpret plasma concentration-time curves and recommend individualized dosing for a drug with narrow therapeutic index.

Describe hygiene measures for preventing healthcare-associated infections, including hand hygiene, isolation precautions, and cleaning of compounding areas.

Outline safe handling procedures for cytotoxic drugs at all stages (receipt, preparation, administration, waste) and the associated monitoring of occupational exposure.

Critically appraise a randomized controlled trial using a standard checklist (e.g., CONSORT) and interpret the results in the context of clinical practice.

Explain basic statistical concepts (p-values, confidence intervals, number needed to treat) and apply them to interpret a published study.

Describe strategies for effective interprofessional collaboration on ward rounds and for teaching pharmacy students and junior staff.

Outline the principles of change management and leadership in a hospital pharmacy setting, including how to implement a quality improvement project.

Review all domains using a self-assessment checklist and identify three areas of weakness for further study.

Complete a timed mock examination covering all domains and analyze incorrect answers to identify knowledge gaps.

Integrate learning from all domains by solving two complex case scenarios that require medication reconciliation, therapeutic drug monitoring, and legal considerations.

Create a personal continuing education plan for the next six months, targeting the identified weaknesses.