CPHON case studies
CPHON · Put your knowledge to work in context.
The Certified Pediatric Hematology Oncology Nurse (CPHON®) credential is a specialty nursing certification administered by the Oncology Nursing Certification Corporation (ONCC). It is designed for registered nurses whose practice focuses on infants, children, and adolescents with hematologic disorders and cancer - a population with distinct physiology, drug handling, and developmental needs that general oncology certification does not address. The CPHON case studies are 5 cases and about 4,111 words.
1New Hypoxemia and "Improving" Leg Pain in a Child With Sickle Cell Disease
Mateo is 7 years old with HbSS, admitted 36 hours ago for a vaso-occlusive pain crisis (bilateral thigh and back pain, 8/10). He is on a morphine PCA and IV fluids at 1x maintenance.
728 words, about 4 min2Delayed Methotrexate Clearance in Interim Maintenance
Priya is 11 years old with B-ALL in interim maintenance. She received high-dose methotrexate 5 g/m2 over 24 hours, and the infusion completed 42 hours ago.
748 words, about 4 min3Opioid Toxicity Versus Uncontrolled Pain in Severe Mucositis
Jonah is 4 years old (16 kg) with high-risk neuroblastoma, day 9 of induction, admitted with grade 3 mucositis. He has a hydromorphone PCA: basal 0.02 mg/kg/hr plus 0.01 mg/kg on demand every 15 minutes, and he has received 14 demands in the last 8 hours.
798 words, about 4 min4Grading CRS After CAR-T Cell Infusion
Amara is 13 years old (45 kg) with relapsed B-ALL, day 4 after tisagenlecleucel infusion. She has had fever 39.8-40.5 C for 18 hours, heart rate 138, and BP 88/48 that rose to 100/60 after one 10 mL/kg normal saline bolus.
824 words, about 4 min5An Adolescent Says He Is Done; His Parents Disagree
Diego is 16 years old with Ewing sarcoma that has progressed through two lines of therapy. Imaging shows new bilateral pulmonary nodules and a new vertebral lesion.
1,013 words, about 5 min