CPHON study materials
CPHON study resources

CPHON study guide

CPHON · Work through your exam, one topic at a time.

The Certified Pediatric Hematology Oncology Nurse (CPHON®) credential is a specialty nursing certification administered by the Oncology Nursing Certification Corporation (ONCC). It is designed for registered nurses whose practice focuses on infants, children, and adolescents with hematologic disorders and cancer - a population with distinct physiology, drug handling, and developmental needs that general oncology certification does not address. The CPHON study guide has 5 sections and about 1,472 words.

01

Care of the Pediatric Patient with Hematologic and Oncologic Disorders

Care of the child with a hematologic or oncologic disorder begins with recognizing that pediatric reference ranges, presentations, and priorities differ from adults. Candidates should know how to interpret a complete blood count using age-specific norms, calculate the absolute neutrophil count, and distinguish expected marrow suppression from urgent complications.

303 words, about 2 min
02

Disease Management and Treatment Modalities

Pediatric cancer treatment is multimodal and protocol-driven. Candidates must understand the purpose of induction, consolidation or intensification, maintenance, and central nervous system prophylaxis in leukemia; surgery, radiation, chemotherapy, targeted agents, immunotherapy, and hematopoietic stem cell transplant in solid tumors and lymphomas.

293 words, about 1 min
03

Supportive Care and Symptom Management

Supportive care is active treatment, not a last resort. Candidates should understand multimodal pain management, scheduled antiemetics, oral care for mucositis, bowel regimens for opioid-induced constipation, nutrition and hydration support, fatigue management, transfusion practice, growth factor use, and prevention of infection.

279 words, about 1 min
04

Oncologic Emergencies and Complications

Oncologic emergencies are time-critical. Candidates must recognize febrile neutropenia, tumor lysis syndrome, hyperleukocytosis and leukostasis, superior vena cava syndrome, spinal cord compression, increased intracranial pressure, hemorrhage and DIC, anaphylaxis, sepsis, typhlitis, and CAR-T-related cytokine release syndrome or neurotoxicity.

299 words, about 1 min
05

Psychosocial, Developmental, and Palliative Care

Psychosocial care is woven through diagnosis, treatment, relapse, survivorship, and end of life. Candidates should understand developmental stages of illness understanding, family systems, sibling needs, school re-entry, fertility preservation, financial and transportation burdens, cultural and spiritual values, and the difference between palliative care and hospice.

298 words, about 1 min