Iran Specialty Board - Emergency Medicine study materials
Iran Specialty Board - Emergency Medicine study resources

Iran Specialty Board - Emergency Medicine key terms

Iran Specialty Board - Emergency Medicine · Get comfortable with the vocabulary.

Septic shock

Life-threatening circulatory failure caused by infection, marked by persistent hypotension needing vasopressors and lactate above 2 mmol/L despite adequate fluid resuscitation, reflecting sepsis-induced vascular and myocardial dysfunction.

Related: Lactate clearance, Norepinephrine first-line, Surviving Sepsis bundle
Lactate clearance

The percentage fall in blood lactate over time, used to gauge adequacy of resuscitation in shock; failure to clear predicts worse outcome and prompts reassessment of perfusion and source control.

Related: Septic shock, Capillary refill time
Norepinephrine first-line

The principle that norepinephrine is the initial vasopressor for septic and most vasodilatory shock, raising mean arterial pressure with less tachyarrhythmia than dopamine and allowing early weaning from fluids.

Related: Septic shock, Permissive hypotension
Permissive hypotension

Deliberately accepting a lower-than-normal blood pressure target during resuscitation, mainly in hemorrhagic trauma, to avoid dislodging clots and worsening bleeding until hemorrhage control is achieved.

Related: Damage control resuscitation, Norepinephrine first-line
Damage control resuscitation

A strategy for major hemorrhage combining early balanced blood products, minimization of crystalloid, permissive hypotension, prevention of hypothermia and acidosis, and rapid surgical or radiologic hemorrhage control.

Related: Permissive hypotension, Massive transfusion protocol, Lethal triad
Massive transfusion protocol

A preplanned, protocolized delivery of large volumes of blood products with balanced ratios, rapid infusers, and laboratory monitoring, activated early in hemorrhagic shock to prevent dilutional coagulopathy and delays.

Related: Damage control resuscitation, Lethal triad
Lethal triad

The self-reinforcing combination of hypothermia, metabolic acidosis, and coagulopathy that drives death in severe trauma; each component worsens the others, so prevention during resuscitation is a core priority.

Related: Damage control resuscitation, Massive transfusion protocol
Focused Assessment with Sonography for Trauma (FAST)

Bedside ultrasound examining pericardial, perihepatic, perisplenic, and pelvic windows for free fluid after blunt trauma; it is rapid, repeatable, and guides operative versus observational decisions.

Related: Extended FAST, Pericardial tamponade
Extended FAST

FAST examination supplemented by thoracic views for hemothorax and pneumothorax, increasing sensitivity for truncal injury without delaying definitive care.

Related: Focused Assessment with Sonography for Trauma (FAST), Tension pneumothorax
Pericardial tamponade

Compression of cardiac chambers by accumulating pericardial fluid, producing hypotension, distended neck veins, and muffled heart sounds; bedside ultrasound shows effusion with chamber collapse and guides urgent drainage.

Related: Pulseless electrical activity, Focused Assessment with Sonography for Trauma (FAST)
Pulseless electrical activity

Cardiac arrest with organized electrical activity on the monitor but no palpable pulse; management targets reversible causes such as hypovolemia, tamponade, tension pneumothorax, thrombosis, and toxins.

Related: Pericardial tamponade, Tension pneumothorax, Point-of-care ultrasound in arrest
Point-of-care ultrasound in arrest

Bedside cardiac and lung ultrasound during resuscitation to distinguish true asystole, detect tamponade, assess ventricular function, and identify reversible causes, while minimizing interruptions in chest compressions.

Related: Pulseless electrical activity, Pericardial tamponade
Tension pneumothorax

Progressive air accumulation in the pleural space causing mediastinal shift and obstructive shock; it is a clinical diagnosis requiring immediate needle decompression or finger thoracostomy before confirmatory imaging.

Related: Extended FAST, Pulseless electrical activity
ST-elevation myocardial infarction

Acute coronary occlusion producing persistent ST elevation in contiguous leads; reperfusion by primary percutaneous coronary intervention or fibrinolysis is time-critical, with emergency department activation of the catheterization pathway.

Related: Door-to-balloon time, Aortic dissection
Door-to-balloon time

Interval from emergency department arrival to first balloon inflation during primary percutaneous coronary intervention; it is a tracked quality metric because shorter times improve survival in ST-elevation myocardial infarction.

Related: ST-elevation myocardial infarction, Clinical audit
Aortic dissection

Tear in the aortic intima allowing blood into the media, causing severe tearing chest or back pain and pulse deficits; management hinges on rapid imaging, blood pressure and rate control, and urgent surgical consultation for type A.

Related: ST-elevation myocardial infarction, Pericardial tamponade
Thrombolysis in ischemic stroke

Intravenous clot-dissolving therapy for acute ischemic stroke within a defined time window after excluding hemorrhage by imaging; benefit is highly time-dependent, so door-to-needle intervals are minimized.

Related: Door-to-needle time, Large vessel occlusion
Door-to-needle time

Interval from hospital arrival to start of intravenous thrombolysis in acute ischemic stroke; a core process measure reflecting triage, imaging speed, and team coordination.

Related: Thrombolysis in ischemic stroke, Clinical audit
Large vessel occlusion

Blockage of a major intracranial artery such as the middle cerebral or basilar artery, producing severe deficits; it may require mechanical thrombectomy and often warrants urgent vascular imaging beyond plain CT.

Related: Thrombolysis in ischemic stroke, National Institutes of Health Stroke Scale
National Institutes of Health Stroke Scale

A standardized 15-item clinical score quantifying stroke severity across consciousness, gaze, vision, motor, sensory, language, and neglect domains; it guides treatment decisions and communication between teams.

Related: Large vessel occlusion, Thrombolysis in ischemic stroke
Status epilepticus

Continuous seizure activity or repeated seizures without recovery lasting about five minutes or more; it is a medical emergency requiring staged benzodiazepine and second-line antiseizure therapy while treating underlying causes.

Related: Nonconvulsive status epilepticus
Nonconvulsive status epilepticus

Prolonged electrographic seizure activity without obvious motor manifestations, presenting as altered consciousness; diagnosis requires electroencephalography and a high index of suspicion in unexplained coma.

Related: Status epilepticus
Acute respiratory distress syndrome

Acute inflammatory lung injury with bilateral opacities and severe hypoxemia not explained by cardiac failure, managed with lung-protective ventilation, prone positioning in severe cases, and treatment of the precipitating cause.

Related: Lung-protective ventilation, Prone positioning
Lung-protective ventilation

Ventilator strategy using low tidal volumes, limited plateau pressures, and appropriate positive end-expiratory pressure to reduce ventilator-induced injury in acute respiratory distress syndrome and other severe lung disease.

Related: Acute respiratory distress syndrome, Prone positioning
Prone positioning

Placing a ventilated patient face down for prolonged periods to improve oxygenation and survival in moderate-to-severe acute respiratory distress syndrome; requires trained teams and attention to pressure areas and lines.

Related: Acute respiratory distress syndrome, Lung-protective ventilation
Rapid sequence intubation

Coordinated administration of a sedative and neuromuscular blocker to secure the airway rapidly while reducing aspiration risk; it includes preoxygenation, hemodynamic optimization, and a planned rescue strategy.

Related: Difficult airway algorithm, Post-intubation hypotension
Difficult airway algorithm

A structured, rehearsed sequence of escalating airway plans used when intubation fails, emphasizing oxygenation over repeated laryngoscopy attempts and early transition to supraglottic or surgical rescue.

Related: Rapid sequence intubation, Cricothyrotomy
Cricothyrotomy

Emergency surgical or needle access through the cricothyroid membrane to establish oxygenation when a cannot-intubate, cannot-oxygenate situation arises; it is a rescue procedure in the difficult airway pathway.

Related: Difficult airway algorithm
Post-intubation hypotension

Fall in blood pressure after induction and positive-pressure ventilation, caused by vasodilation, hypovolemia, or reduced venous return; it requires prompt fluid, vasopressor, or sedative adjustment to prevent arrest.

Related: Rapid sequence intubation
Sepsis in the febrile infant

Suspected systemic infection in a young infant with fever, prompting age-based evaluation and empirical antibiotics because clinical signs are unreliable and serious bacterial infection risk is high in the youngest.

Related: Septic shock, Pediatric early warning score
Pediatric early warning score

A bedside scoring tool combining vital signs and observational items to flag hospitalized children at risk of deterioration, triggering escalation of care before overt clinical collapse.

Related: Sepsis in the febrile infant, Rapid response team
Postpartum hemorrhage

Excessive blood loss after delivery, most often from uterine atony; management proceeds through uterine massage, uterotonics, tranexamic acid, and escalating mechanical or surgical measures while resuscitating.

Related: Massive transfusion protocol, Ectopic pregnancy
Ectopic pregnancy

Implantation of the embryo outside the uterine cavity, typically in a fallopian tube; it can rupture causing hemoperitoneum and shock, so pregnancy testing and pelvic ultrasound are central in abdominal pain of reproductive-age patients.

Related: Postpartum hemorrhage, Focused Assessment with Sonography for Trauma (FAST)
Preeclampsia with severe features

Hypertensive disorder of pregnancy with proteinuria or end-organ dysfunction such as thrombocytopenia, liver enzyme elevation, renal impairment, or neurologic symptoms; management includes magnesium sulfate and timely delivery.

Related: Postpartum hemorrhage
Toxidrome

A recognizable constellation of clinical signs suggesting a specific class of poisoning, such as anticholinergic, cholinergic, opioid, sympathomimetic, or sedative-hypnotic patterns, guiding empiric treatment before laboratory confirmation.

Related: Naloxone, Serotonin syndrome
Naloxone

Competitive opioid receptor antagonist used to reverse opioid-induced respiratory depression; titrated doses restore breathing while avoiding abrupt withdrawal and recurrent sedation from short duration of action.

Related: Toxidrome
Serotonin syndrome

Drug-induced excess serotonergic activity causing agitation, clonus, hyperreflexia, and hyperthermia; treatment is supportive with cessation of offending agents, benzodiazepines, and cooling in severe cases.

Related: Toxidrome, Neuroleptic malignant syndrome
Neuroleptic malignant syndrome

Idiosyncratic reaction to dopamine antagonists causing rigidity, hyperthermia, autonomic instability, and elevated creatine kinase; management includes stopping the drug, supportive care, and sometimes dantrolene or bromocriptine.

Related: Serotonin syndrome
Triage in mass casualty incidents

Rapid sorting of casualties by physiologic and anatomic criteria into treatment priorities so limited resources save the most lives; it is repeated as patients change and must be simple and practiced.

Related: Surge capacity, Hospital incident command system
Surge capacity

The ability of a health system to expand staff, space, supplies, and services beyond normal operations during a disaster or mass casualty event, planned in advance through escalation tiers and memoranda of understanding.

Related: Triage in mass casualty incidents, Hospital incident command system
Hospital incident command system

A standardized command structure assigning roles for operations, planning, logistics, and finance during emergencies, enabling clear authority, communication, and coordination with external agencies.

Related: Surge capacity, Triage in mass casualty incidents
Informed consent in the emergency department

Obtaining permission for treatment after explaining risks, benefits, and alternatives; emergency exceptions permit lifesaving care when the patient cannot consent and no surrogate is available.

Related: Decisional capacity
Decisional capacity

A patient's ability to understand information, appreciate consequences, reason about options, and communicate a choice; it is assessed for specific decisions and is distinct from legal competence.

Related: Informed consent in the emergency department
Clinical audit

Systematic comparison of current practice against agreed standards, followed by feedback and re-measurement to close the gap; it is a core quality improvement method in emergency departments.

Related: Plan-Do-Study-Act cycle, Door-to-balloon time
Plan-Do-Study-Act cycle

Iterative improvement method in which a small change is planned, tested, studied for effects, and acted upon, then scaled or revised; it supports rapid, low-risk learning in clinical systems.

Related: Clinical audit, Rapid response team
Number needed to treat

The number of patients who must receive an intervention for one additional patient to benefit, calculated as the reciprocal of absolute risk reduction; it translates trial results into practical clinical impact.

Related: Confidence interval, Clinical audit
Confidence interval

A range of values around an estimate that is likely to contain the true effect with a stated probability; its width conveys precision and helps judge whether findings are clinically meaningful.

Related: Number needed to treat
Rapid response team

A team summoned by ward staff when a patient meets deterioration criteria, bringing critical care expertise to the bedside early; it aims to prevent cardiac arrest and unplanned intensive care admission.

Related: Pediatric early warning score, Plan-Do-Study-Act cycle