Iran Pharm.D. End-of-Course Exam case studies
Iran Pharm.D. End-of-Course Exam · Put your knowledge to work in context.
End-of-Course Exam (امتحان جامع دکتری داروسازی) is the comprehensive assessment that Iranian pharmacy schools use to confirm a Doctor of Pharmacy candidate has integrated the full curriculum before graduation and entry into practice. It is aimed at students who have finished the didactic and practical coursework of the Pharm.D. The Iran Pharm.D. End-of-Course Exam case studies are 5 cases and about 2,645 words.
1Ethanol-Induced Dose Dumping After a Viscosity-Grade Change in an Extended-Release Matrix
A generic manufacturer proposes substituting hypromellose K100M with K4M in a 200 mg extended-release matrix tablet of metoprolol succinate to reduce cost. In vitro dissolution in 0.1 N HCl for 2 h then pH 6.8 buffer shows: at 2 h, 42% released (reference 18%); at 6 h, 78% (reference 48%); at 12 h, 96% (reference 78%).
494 words, about 2 min2Atropine Titration and Oxime Timing in Occupational Chlorpyrifos Poisoning
A 24-year-old farm worker is brought to a rural emergency department 4 hours after spraying chlorpyrifos without protective equipment. He has pinpoint pupils of 2 mm, profuse salivation, bronchorrhea, bradycardia of 48 beats/min, fasciculations in the calves, confusion, and vomiting.
526 words, about 3 min3Apixaban Dosing and Hyperkalemia in an Older Adult with HFrEF and CKD
A 78-year-old woman weighing 55 kg with heart failure and reduced ejection fraction (EF 30%) and atrial fibrillation is admitted with dizziness and poor oral intake. Her serum creatinine is 1.7 mg/dL (baseline 1.5 mg/dL), potassium 5.9 mEq/L, and eGFR 24 mL/min/1.73 m².
545 words, about 3 min4Secondary Loss of Response to an Infliximab Biosimilar with Anti-Drug Antibodies
A 52-year-old man with ileocolonic Crohn's disease has been receiving an infliximab biosimilar at 5 mg/kg every 8 weeks for 14 months. He initially had a clinical response and a normal C-reactive protein.
548 words, about 3 min5Out-of-Specification HPLC Assay with a Failed System Suitability Run
A quality control laboratory is assaying a 500 mg metformin hydrochloride extended-release tablet by HPLC. The first injection sequence gives an assay result of 92.5% of label claim, with an unspecified impurity at 0.42%.
532 words, about 3 min