Iran Pharm.D. End-of-Course Exam study plan

Map the Pharmaceutics syllabus into unit operations, dosage-form design, and stability, then rank each subtopic by exam weight

Derive and apply the Noyes-Whitney, Higuchi, and zero/first-order release equations to numerical problems without notes

Classify 20 excipients by functional role (binder, disintegrant, lubricant, glidant, coating) and state one incompatibility for each

Interpret a full HPLC assay validation set (accuracy, precision, LOD/LOQ, linearity) against acceptance criteria

Solve 15 pharmacopeial calculation items covering content uniformity, dissolution Q-value, and % label claim

Compare tablet, capsule, parenteral, semisolid, and modified-release systems by manufacturing route and critical quality attributes

Explain how particle size, polymorphism, and hygroscopicity change bioavailability and processability

Outline sterilization methods (moist heat, dry heat, filtration, radiation, aseptic) with parameters and material suitability

Diagnose 10 given manufacturing defects (capping, lamination, picking, creaming, phase separation) and propose a corrective action for each

Apply ICH Q1A stability zone conditions to design a 6-month accelerated study for a hygroscopic product

Draw dose-response curves and distinguish potency, efficacy, slope, and therapeutic index with worked examples

Trace autonomic pharmacology receptor by receptor (muscarinic, nicotinic, alpha-1/2, beta-1/2/3) to organ-level response

Link each major organ system's normal physiology to at least two pathophysiological states and their pharmacological targets

Calculate loading dose, maintenance dose, clearance, and half-life from given pharmacokinetic parameters

Classify antidotes and chelators by toxin class and state the mechanism of each

Explain toxicokinetics: absorption enhancement, metabolic activation, and enterohepatic recycling of poisons

Interpret liver and kidney function panels (ALT, AST, ALP, bilirubin, creatinine, eGFR, BUN) and predict how each alters drug dosing

Describe cardiac, hepatic, and renal biomarkers and the clinical decision each triggers

Work through 10 overdose scenarios selecting decontamination, enhanced elimination, or antidote therapy

Correlate electrolyte and acid-base disturbances with their pharmacological causes and corrections

Build guideline-based treatment algorithms for hypertension, type 2 diabetes, heart failure, asthma/COPD, and dyslipidemia

Apply Beers and STOPP criteria to deprescribe in a supplied 80-year-old polypharmacy case

Adjust regimens for renal and hepatic impairment, pregnancy, and pediatrics using explicit dosing rules

Detect and classify 10 drug-drug interactions by mechanism (CYP inhibition/induction, protein binding, pharmacodynamic) and propose management

Construct a SOAP note and patient counseling script for a newly diagnosed chronic disease

Explain Iran's drug scheduling, narcotics regulations, and pharmacovigilance reporting pathways as tested on the exam

Distinguish bioequivalence, therapeutic equivalence, and generic substitution rules and apply them to product selection

Calculate cost-effectiveness, number needed to treat, and absolute risk reduction from trial data

Draft a pharmaceutical care plan that documents interventions, adherence support, and outcome measures

Analyze dispensing-error and medication-safety scenarios using root-cause reasoning

Map functional groups to physicochemical properties, receptor binding, and metabolic soft spots for 25 major drug classes

Apply prodrug, bioisostere, and structure-activity relationship logic to explain why two analogues differ in potency or duration

Identify 20 major medicinal plants by active constituent, class, and documented pharmacological use

Explain biotechnological product classes (monoclonal antibodies, insulin analogues, vaccines, biosimilars) and their immunogenicity and stability concerns

Relate Biopharmaceutics Classification System class to dissolution specification, food effect, and formulation strategy

Sit two full-length mixed mock exams under timed conditions and record per-domain accuracy

Re-drill every missed item from weeks 1-7 until each is answered correctly twice on separate days

Recite from memory the top 50 high-yield facts spanning calculations, antidotes, dosing rules, and regulations

Rehearse calculation speed: complete 20 pharmaceutical and pharmacokinetic calculations in 40 minutes

Finalize a one-page pre-exam summary sheet organized by domain weight