Facharzt FMH Pathologie - independent subject foundations cheat sheet

Relate biopsy depth and sampling to the conclusions the specimen can support.

Integrate architecture and invasion rather than diagnose from atypia alone.

Use organ-specific immunopanel and biomarker criteria.

MMR protein loss can direct further investigation without independently proving an inherited syndrome.

Integrate morphology with a suitable panel rather than one universal marker.

Keep cytology classification separate from proving stromal invasion.

Distinguish thyroid and cervical reporting systems and editions.

Absent sampled detrusor does not exclude deeper bladder invasion elsewhere.

Preserve tissue while selecting markers for a real differential.

Do not diagnose a completely noninvasive lung tumor from one small sampled focus.

Mesothelial lineage and malignant behavior are different questions.

Integrate matrix, anatomy and molecular evidence in soft-tissue and bone lesions.

A lineage marker does not independently prove malignancy.

FNA cannot establish every capsular, vascular or stromal relationship.

Use integrated molecular and morphological classification in neuropathology.

Report uncertainty, sampling limits and prognosis without deterministic promises.

Match the specimen type to the architectural information required.

MYC, CD30 and BCL2-associated findings are not universal stand-alone subtype definitions.

Apply the actual blast, genetic and exclusion criteria for the named marrow entity.

Connect morphology with clinical laboratory evidence and communicate urgent findings appropriately.

Use preparation-specific adequacy and the actual reporting system.

A failed control can make a negative result uninterpretable.

A circulating mutation does not identify its cellular origin without sufficient evidence.

Separate quality metrics, autopsy mechanisms and local legal determinations.