Facharzt FMH Pathologie - independent subject foundations common mistakes
Facharzt FMH Pathologie - independent subject foundations · Understand the traps and how to avoid them.
Reading every transmural finding into a superficial biopsy
The sampled material may not include the tissue layer required for that conclusion.
What to do instead
State specimen depth and distinguish the actual findings from a resection pattern.
Calling an isolated marker proof of lineage and malignancy
Different lesions can share markers, and lineage does not by itself establish behavior.
What to do instead
Use morphology, a relevant panel and the clinical setting.
Diagnosing absence of invasion from one lepidic core
Unsampled regions may contain invasive growth.
What to do instead
Use a specimen and framework capable of establishing the complete category.
Applying a breast handling window to every assay
Specimen and analyte requirements can differ.
What to do instead
Follow the validated organ- and assay-specific process rather than a universal copied number.
Equating MLH1/PMS2 loss with proven Lynch syndrome
Sporadic mechanisms can produce the same loss pattern.
What to do instead
Use the appropriate reflex and inherited-risk assessment with valid controls.
Calling every DNMT3A plasma variant proven CHIP
A gene association alone does not establish the actual source in an individual.
What to do instead
Assess paired samples, tumor results and the relevant clinical context.
Using cytology alone to prove every stromal relationship
Dispersed cells do not preserve all the architecture required for certain categories.
What to do instead
Report the appropriate category and sampling limitations.
Confusing a disease finding with a legally determined manner of death
Scene, medical, ancillary and jurisdictional evidence can be required.
What to do instead
Keep medical observations, mechanism, cause and legal determination distinct.